CRCGN013_HEPG2_24H:C01 Gene Set
Genes
48 genes differentially expressed following the CRCGN013_HEPG2_24H:C01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
6.40756
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.57796
|
|
LAGE3
|
L antigen family, member 3
|
3.59632
|
|
CYCS
|
cytochrome c, somatic
|
2.80244
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
2.61007
|
|
VAV3
|
vav 3 guanine nucleotide exchange factor
|
2.59345
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.45685
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.39351
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
2.39329
|
|
SFTPB
|
surfactant protein B
|
2.37501
|
|
FASTKD5
|
FAST kinase domains 5
|
2.35787
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
2.32797
|
|
TCTA
|
T-cell leukemia translocation altered
|
2.21868
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.17594
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
2.15369
|
|
FCHO1
|
FCH domain only 1
|
2.13717
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.12744
|
|
CXCR4
|
chemokine (C-X-C motif) receptor 4
|
2.11773
|
|
TBP
|
TATA box binding protein
|
2.08798
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.05213
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.04699
|
|
OAS3
|
2'-5'-oligoadenylate synthetase 3, 100kDa
|
2.02927
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.02346
|
|
MMP2
|
matrix metallopeptidase 2
|
2.01219
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-4.20875
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-3.85062
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.80341
|
|
THAP11
|
THAP domain containing 11
|
-3.67687
|
|
INPP1
|
inositol polyphosphate-1-phosphatase
|
-3.62782
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.5606
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.16015
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.04885
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.00184
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.77205
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.75414
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.72572
|
|
LOC124907782
|
dual specificity protein phosphatase 22
|
-2.66431
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.63376
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.6144
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.48774
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.48218
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.47995
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.46416
|
|
DUSP6
|
dual specificity phosphatase 6
|
-2.38006
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.34751
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.14781
|
|
MTA1
|
metastasis associated 1
|
-2.04051
|
|
CCNB1
|
cyclin B1
|
-2.03108
|
