CRCGN013_HEPG2_24H:C02 Gene Set
Genes
32 genes differentially expressed following the CRCGN013_HEPG2_24H:C02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
4.9018
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.51131
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.34193
|
|
STAP2
|
signal transducing adaptor family member 2
|
4.30569
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.12691
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.02947
|
|
FZD7
|
frizzled class receptor 7
|
3.18947
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.75156
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.71531
|
|
CCNF
|
cyclin F
|
2.71217
|
|
KIF20A
|
kinesin family member 20A
|
2.69182
|
|
TBXA2R
|
thromboxane A2 receptor
|
2.21046
|
|
PTPN3
|
protein tyrosine phosphatase, non-receptor type 3
|
2.14266
|
|
CDK8
|
cyclin-dependent kinase 8
|
2.01006
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-7.07816
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-6.85054
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.87249
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.70078
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-4.59592
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.10944
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.0607
|
|
ADI1
|
acireductone dioxygenase 1
|
-4.02785
|
|
ISOC1
|
isochorismatase domain containing 1
|
-3.91574
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.14553
|
|
GNAS
|
GNAS complex locus
|
-3.11897
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.98704
|
|
WASHC4
|
WASH complex subunit 4
|
-2.972
|
|
SNX11
|
sorting nexin 11
|
-2.9464
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.72374
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.59794
|
|
EGF
|
epidermal growth factor
|
-2.23129
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.1938
|
