CRCGN013_HEPG2_24H:C04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-nitroanthranilic acid 5.07 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN013_HEPG2_24H:C04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 5.29329
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 4.42548
IKZF1 IKAROS family zinc finger 1 (Ikaros) 4.31555
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.85255
CIAO3 cytosolic iron-sulfur assembly component 3 3.71966
LCN2 lipocalin 2 3.56821
CCNF cyclin F 3.52712
NFIL3 nuclear factor, interleukin 3 regulated 3.35723
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 3.18879
STK10 serine/threonine kinase 10 3.09089
CXCR4 chemokine (C-X-C motif) receptor 4 3.05519
TIAM1 T-cell lymphoma invasion and metastasis 1 2.93407
MAP7 microtubule-associated protein 7 2.89552
ABHD6 abhydrolase domain containing 6 2.85868
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 2.5729
UBQLN2 ubiquilin 2 2.5292
STX1A syntaxin 1A (brain) 2.52356
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 2.52074
PRR15L proline rich 15-like 2.14718
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 2.10443
ADAT1 adenosine deaminase, tRNA-specific 1 2.08836

decreased expression

Symbol Name Standardized Value
NGRN neugrin, neurite outgrowth associated -3.07478
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.01095
RFC2 replication factor C (activator 1) 2, 40kDa -2.92633
NRIP1 nuclear receptor interacting protein 1 -2.77807
ELAC2 elaC ribonuclease Z 2 -2.75373
TLCD3A TLC domain containing 3A -2.73091
CAB39 calcium binding protein 39 -2.52176
RNF167 ring finger protein 167 -2.39133
LRPAP1 low density lipoprotein receptor-related protein associated protein 1 -2.29138
TXNDC9 thioredoxin domain containing 9 -2.17113
CCNB2 cyclin B2 -2.15165
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -2.1199
OXA1L oxidase (cytochrome c) assembly 1-like -2.06604
CCP110 centriolar coiled coil protein 110kDa -2.06257