CRCGN013_HEPG2_24H:C06 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description 4-nitroanthranilic acid 1.27 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

35 genes differentially expressed following the CRCGN013_HEPG2_24H:C06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 5.84808
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 4.34977
PPARG peroxisome proliferator-activated receptor gamma 3.91571
RPP38 ribonuclease P/MRP 38kDa subunit 3.66389
TBP TATA box binding protein 3.33122
SFTPB surfactant protein B 3.02027
CBR3 carbonyl reductase 3 3.00596
PFKL phosphofructokinase, liver 2.94128
PPP1R13B protein phosphatase 1, regulatory subunit 13B 2.88175
SSBP2 single-stranded DNA binding protein 2 2.69115
NOSIP nitric oxide synthase interacting protein 2.59877
GPER1 G protein-coupled estrogen receptor 1 2.59081
CHN1 chimerin 1 2.47606
CHMP6 charged multivesicular body protein 6 2.38056
EGF epidermal growth factor 2.36576
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 2.3232
JADE2 jade family PHD finger 2 2.28623
CDK19 cyclin-dependent kinase 19 2.19245
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 2.16789
HOXA10 homeobox A10 2.15071
ADAT1 adenosine deaminase, tRNA-specific 1 2.11521
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 2.11338
SIRT3 sirtuin 3 2.10748
RRAGA Ras-related GTP binding A 2.08562
ST20-MTHFS ST20-MTHFS readthrough 2.03026

decreased expression

Symbol Name Standardized Value
GNAS GNAS complex locus -4.51823
CASP7 caspase 7, apoptosis-related cysteine peptidase -4.25241
OXA1L oxidase (cytochrome c) assembly 1-like -4.07756
CDC20 cell division cycle 20 -3.89826
C2CD5 C2 calcium-dependent domain containing 5 -3.56983
FGFR4 fibroblast growth factor receptor 4 -3.46207
LDHD lactate dehydrogenase D -3.07747
CCNB1 cyclin B1 -2.87152
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -2.14806
CCNB2 cyclin B2 -2.02228