CRCGN013_HEPG2_24H:C07 Gene Set
Genes
39 genes differentially expressed following the CRCGN013_HEPG2_24H:C07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
7.36416
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
4.45948
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.27954
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
4.07551
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.82825
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
3.6717
|
|
CCNH
|
cyclin H
|
3.57041
|
|
LCN2
|
lipocalin 2
|
3.52156
|
|
STK10
|
serine/threonine kinase 10
|
3.49553
|
|
EPN2
|
epsin 2
|
2.74621
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
2.57666
|
|
RRAGA
|
Ras-related GTP binding A
|
2.55566
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.50253
|
|
CYCS
|
cytochrome c, somatic
|
2.40513
|
|
MCOLN1
|
mucolipin 1
|
2.38869
|
|
PFKL
|
phosphofructokinase, liver
|
2.36676
|
|
SIRT3
|
sirtuin 3
|
2.34311
|
|
NCK1
|
NCK adaptor protein 1
|
2.19449
|
|
KIF20A
|
kinesin family member 20A
|
2.17559
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.08004
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.00381
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-5.82595
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.78881
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.96975
|
|
STUB1
|
STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
|
-3.85714
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.61222
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.4629
|
|
HEATR1
|
HEAT repeat containing 1
|
-3.24515
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.22786
|
|
RRP12
|
ribosomal RNA processing 12 homolog (S. cerevisiae)
|
-3.12178
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.02375
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.99014
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.5663
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-2.38018
|
|
GNAS
|
GNAS complex locus
|
-2.35798
|
|
RNF167
|
ring finger protein 167
|
-2.28353
|
|
TEX10
|
testis expressed 10
|
-2.06682
|
|
AMIGO2
|
adhesion molecule with Ig-like domain 2
|
-2.04679
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.00924
|
