| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | paracetamol 20.6 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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53 genes differentially expressed following the CRCGN013_HEPG2_24H:C08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PPARG | peroxisome proliferator-activated receptor gamma | 9.332 |
| GPER1 | G protein-coupled estrogen receptor 1 | 5.37523 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 5.07427 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.84474 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.52972 |
| MOK | MOK protein kinase | 4.14967 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 4.0908 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 3.8456 |
| RRAGA | Ras-related GTP binding A | 3.57185 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | 3.54633 |
| PFKL | phosphofructokinase, liver | 3.40783 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.27899 |
| SFTPB | surfactant protein B | 3.1787 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 3.0821 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | 3.05438 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 2.94635 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 2.61656 |
| SSBP2 | single-stranded DNA binding protein 2 | 2.54161 |
| PRR15L | proline rich 15-like | 2.52676 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | 2.49085 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.38209 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.18203 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.15746 |
| FPGS | folylpolyglutamate synthase | 2.13256 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 | 2.10696 |
| KLHDC3 | kelch domain containing 3 | 2.08881 |
| GATD3 | glutamine amidotransferase class 1 domain containing 3 | 2.07472 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 2.05318 |
| FBXO5 | F-box protein 5 | 2.04338 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CCNB2 | cyclin B2 | -7.04573 |
| HSPB1 | heat shock 27kDa protein 1 | -4.7379 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -4.58166 |
| RAI14 | retinoic acid induced 14 | -4.50435 |
| CDC20 | cell division cycle 20 | -4.45575 |
| MRPS2 | mitochondrial ribosomal protein S2 | -4.32329 |
| VAT1 | vesicle amine transport 1 | -4.28177 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.96484 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.91895 |
| GNAS | GNAS complex locus | -3.2751 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.19623 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.03749 |
| ZNF586 | zinc finger protein 586 | -3.007 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -2.69075 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -2.20277 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.16942 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 | -2.16298 |
| PRTN3 | proteinase 3 | -2.14159 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.0635 |
| POLR2M | polymerase (RNA) II (DNA directed) polypeptide M | -2.05201 |
| XPNPEP2 | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound | -2.05035 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -2.04014 |
| TAC1 | tachykinin, precursor 1 | -2.03854 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.03383 |
