CRCGN013_HEPG2_24H:C09 Gene Set
Genes
50 genes differentially expressed following the CRCGN013_HEPG2_24H:C09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
E2F2
|
E2F transcription factor 2
|
6.53931
|
|
LCN2
|
lipocalin 2
|
5.37072
|
|
STIMATE
|
STIM activating enhancer
|
4.48475
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.44008
|
|
CHN1
|
chimerin 1
|
4.27644
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.71456
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.6514
|
|
MAP7
|
microtubule-associated protein 7
|
3.60225
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.5428
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.35142
|
|
MCM3
|
minichromosome maintenance complex component 3
|
3.21304
|
|
SFTPB
|
surfactant protein B
|
3.00631
|
|
FCHO1
|
FCH domain only 1
|
2.97012
|
|
FPGS
|
folylpolyglutamate synthase
|
2.76338
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.7458
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.53168
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.52451
|
|
SCRN1
|
secernin 1
|
2.47915
|
|
GATA3
|
GATA binding protein 3
|
2.43205
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.40853
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.2288
|
|
TBP
|
TATA box binding protein
|
2.10393
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NGRN
|
neugrin, neurite outgrowth associated
|
-5.71516
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-5.39396
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-4.40199
|
|
VAT1
|
vesicle amine transport 1
|
-4.38886
|
|
ZNF586
|
zinc finger protein 586
|
-4.21123
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.11703
|
|
PEG10
|
paternally expressed 10
|
-4.05552
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.87933
|
|
PLK1
|
polo-like kinase 1
|
-3.79722
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.77968
|
|
LDHD
|
lactate dehydrogenase D
|
-3.65174
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.58974
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.51916
|
|
GOLT1B
|
golgi transport 1B
|
-3.44714
|
|
TRAPPC3
|
trafficking protein particle complex 3
|
-3.4456
|
|
CRELD2
|
cysteine-rich with EGF-like domains 2
|
-2.87356
|
|
EGF
|
epidermal growth factor
|
-2.7164
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.61316
|
|
FAM13A
|
family with sequence similarity 13, member A
|
-2.4196
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.34158
|
|
LTA4H
|
leukotriene A4 hydrolase
|
-2.33517
|
|
FXYD5
|
FXYD domain containing ion transport regulator 5
|
-2.23842
|
|
CCNB1
|
cyclin B1
|
-2.20376
|
|
GRN
|
granulin
|
-2.17564
|
|
ITGB1BP1
|
integrin beta 1 binding protein 1
|
-2.09505
|
|
LMBR1L
|
limb development membrane protein 1-like
|
-2.0597
|
|
STUM
|
stum, mechanosensory transduction mediator homolog
|
-2.02636
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.00501
|
