CRCGN013_HEPG2_24H:C10 Gene Set
Genes
38 genes differentially expressed following the CRCGN013_HEPG2_24H:C10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
10.0
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
4.13412
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.78583
|
|
CBR3
|
carbonyl reductase 3
|
3.70182
|
|
UBQLN2
|
ubiquilin 2
|
3.35349
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
3.24086
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
3.17682
|
|
CYCS
|
cytochrome c, somatic
|
3.09666
|
|
HEBP1
|
heme binding protein 1
|
3.08571
|
|
PRR15L
|
proline rich 15-like
|
2.89217
|
|
MOK
|
MOK protein kinase
|
2.86724
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.85388
|
|
MNAT1
|
MNAT CDK-activating kinase assembly factor 1
|
2.74406
|
|
LCN2
|
lipocalin 2
|
2.68134
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.59036
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.52619
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
2.48183
|
|
PROS1
|
protein S (alpha)
|
2.37208
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.29894
|
|
TBP
|
TATA box binding protein
|
2.26879
|
|
MORC3
|
MORC family CW-type zinc finger 3
|
2.07881
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.49572
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-6.26506
|
|
TLCD3A
|
TLC domain containing 3A
|
-5.73748
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.00224
|
|
GNAS
|
GNAS complex locus
|
-4.43229
|
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-4.01584
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-3.63843
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.47531
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.25716
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.06529
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.00619
|
|
CCNB1
|
cyclin B1
|
-2.62778
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.61589
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-2.58491
|
|
HMG20B
|
high mobility group 20B
|
-2.43973
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.30733
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.30348
|
