CRCGN013_HEPG2_24H:C13 Gene Set
Genes
42 genes differentially expressed following the CRCGN013_HEPG2_24H:C13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PLS1
|
plastin 1
|
3.62653
|
|
MYLK
|
myosin light chain kinase
|
3.56596
|
|
UBQLN2
|
ubiquilin 2
|
3.50498
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
3.47274
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.30015
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.2709
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
3.25745
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.12944
|
|
LCN2
|
lipocalin 2
|
2.73592
|
|
VAT1
|
vesicle amine transport 1
|
2.55341
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.534
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.49409
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.40545
|
|
FZD7
|
frizzled class receptor 7
|
2.37824
|
|
IFIT1
|
interferon-induced protein with tetratricopeptide repeats 1
|
2.35358
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
2.29535
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.27319
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.23819
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.236
|
|
RIGI
|
RNA sensor RIG-I
|
2.17376
|
|
PMM2
|
phosphomannomutase 2
|
2.08596
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
2.02803
|
|
FPGS
|
folylpolyglutamate synthase
|
2.00166
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-4.9321
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-4.79276
|
|
ZNF586
|
zinc finger protein 586
|
-3.75948
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.65806
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.99341
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-2.83529
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.83484
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.62627
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.60389
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-2.48478
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.29383
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.2226
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.15741
|
|
CDC25B
|
cell division cycle 25B
|
-2.14866
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.14414
|
|
ANGPTL4
|
angiopoietin-like 4
|
-2.07896
|
|
HAGH
|
hydroxyacylglutathione hydrolase
|
-2.04694
|
|
BATF
|
basic leucine zipper transcription factor, ATF-like
|
-2.0188
|
|
SNX11
|
sorting nexin 11
|
-2.00146
|