CRCGN013_HEPG2_24H:C14 Gene Set
Genes
41 genes differentially expressed following the CRCGN013_HEPG2_24H:C14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
6.98227
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
4.59557
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.47787
|
|
UBQLN2
|
ubiquilin 2
|
4.32535
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.02437
|
|
TBP
|
TATA box binding protein
|
3.08375
|
|
FZD7
|
frizzled class receptor 7
|
3.02563
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.98019
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.92668
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.70072
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.61848
|
|
POLE2
|
polymerase (DNA directed), epsilon 2, accessory subunit
|
2.5717
|
|
PMM2
|
phosphomannomutase 2
|
2.53315
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.4497
|
|
MYLK
|
myosin light chain kinase
|
2.40871
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.32255
|
|
CEMIP2
|
cell migration inducing hyaluronidase 2
|
2.20339
|
|
SFTPB
|
surfactant protein B
|
2.0949
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.19927
|
|
CCNB2
|
cyclin B2
|
-5.03143
|
|
CCNB1
|
cyclin B1
|
-4.70132
|
|
CD320
|
CD320 molecule
|
-4.63776
|
|
GDF15
|
growth differentiation factor 15
|
-4.52114
|
|
LDHD
|
lactate dehydrogenase D
|
-4.45071
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.27201
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.73743
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.55257
|
|
GOLT1B
|
golgi transport 1B
|
-3.25937
|
|
TP53BP2
|
tumor protein p53 binding protein 2
|
-3.15454
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.0373
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.03051
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.8149
|
|
CALML4
|
calmodulin-like 4
|
-2.65941
|
|
CDC20
|
cell division cycle 20
|
-2.49774
|
|
ATP6V1D
|
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
|
-2.42492
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.3315
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.28322
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.22438
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-2.21043
|
|
INSIG1
|
insulin induced gene 1
|
-2.20309
|
|
FHL2
|
four and a half LIM domains 2
|
-2.13633
|
