CRCGN013_HEPG2_24H:C15 Gene Set
Genes
52 genes differentially expressed following the CRCGN013_HEPG2_24H:C15 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PRR15L
|
proline rich 15-like
|
4.34749
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.62567
|
|
LCN2
|
lipocalin 2
|
3.46933
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.43499
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.27484
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.24224
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.16917
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.15688
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
3.09815
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.04177
|
|
LOC122526780
|
uncharacterized LOC122526780
|
3.00001
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.97336
|
|
CBR3
|
carbonyl reductase 3
|
2.9625
|
|
E2F2
|
E2F transcription factor 2
|
2.85226
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.82819
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.66996
|
|
CCNA1
|
cyclin A1
|
2.63304
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.60538
|
|
EGF
|
epidermal growth factor
|
2.43892
|
|
TAB1
|
TGF-beta activated kinase 1/MAP3K7 binding protein 1
|
2.31291
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
2.29964
|
|
KIF20A
|
kinesin family member 20A
|
2.17486
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.05015
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.00618
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-6.84733
|
|
CCNB2
|
cyclin B2
|
-4.26887
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.63567
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.44267
|
|
SCAND1
|
SCAN domain containing 1
|
-3.20903
|
|
ZNF134
|
zinc finger protein 134
|
-3.15912
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.12364
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.09946
|
|
LSM5
|
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
|
-3.09454
|
|
DSG2
|
desmoglein 2
|
-3.01848
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.95559
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.85663
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.69406
|
|
GNAS
|
GNAS complex locus
|
-2.41269
|
|
ZNF587B
|
zinc finger protein 587B
|
-2.40934
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.38476
|
|
RNF167
|
ring finger protein 167
|
-2.35258
|
|
CCNB1
|
cyclin B1
|
-2.31347
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.28105
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.24802
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.23073
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.18135
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.16805
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.14858
|
|
ZNF587
|
zinc finger protein 587
|
-2.13958
|
|
ZNF551
|
zinc finger protein 551
|
-2.11996
|
|
TMEM109
|
transmembrane protein 109
|
-2.105
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.06553
|