CRCGN013_HEPG2_24H:C16 Gene Set
Genes
44 genes differentially expressed following the CRCGN013_HEPG2_24H:C16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
5.55624
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.44086
|
|
RPL39L
|
ribosomal protein L39-like
|
3.35428
|
|
MAMLD1
|
mastermind-like domain containing 1
|
3.26876
|
|
JADE2
|
jade family PHD finger 2
|
3.24103
|
|
RRAGA
|
Ras-related GTP binding A
|
3.20805
|
|
GATA3
|
GATA binding protein 3
|
2.97864
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.91873
|
|
LCN2
|
lipocalin 2
|
2.85564
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
2.78682
|
|
NOTCH1
|
notch 1
|
2.66563
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.65655
|
|
NUP133
|
nucleoporin 133kDa
|
2.56761
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.50813
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.46041
|
|
EDEM1
|
ER degradation enhancer, mannosidase alpha-like 1
|
2.33307
|
|
CRTAP
|
cartilage associated protein
|
2.3006
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.29532
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.28104
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.15467
|
|
CCNF
|
cyclin F
|
2.12335
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.09166
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.08599
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.06515
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.00436
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC35F2
|
solute carrier family 35, member F2
|
-4.51614
|
|
GOLT1B
|
golgi transport 1B
|
-4.32243
|
|
LDHD
|
lactate dehydrogenase D
|
-4.28996
|
|
GNAS
|
GNAS complex locus
|
-4.25673
|
|
C5
|
complement component 5
|
-4.2344
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-4.11359
|
|
DSG2
|
desmoglein 2
|
-3.71136
|
|
ZNF586
|
zinc finger protein 586
|
-3.37102
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.96051
|
|
TCERG1
|
transcription elongation regulator 1
|
-2.83373
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.74653
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.69341
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.64252
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.63324
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.35967
|
|
HMG20B
|
high mobility group 20B
|
-2.33647
|
|
PEG10
|
paternally expressed 10
|
-2.32495
|
|
ISOC1
|
isochorismatase domain containing 1
|
-2.18999
|
|
ALDH7A1
|
aldehyde dehydrogenase 7 family, member A1
|
-2.14874
|
