CRCGN013_HEPG2_24H:C18 Gene Set
Genes
40 genes differentially expressed following the CRCGN013_HEPG2_24H:C18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
4.46177
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
3.56407
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
3.40617
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.3175
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.10913
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
3.04043
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.9928
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.40873
|
|
EPHA3
|
EPH receptor A3
|
2.36698
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.27228
|
|
CYCS
|
cytochrome c, somatic
|
2.26297
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.14383
|
|
PTK2
|
protein tyrosine kinase 2
|
2.13608
|
|
PROS1
|
protein S (alpha)
|
2.04133
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.00007
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-6.5057
|
|
CCNB2
|
cyclin B2
|
-4.88563
|
|
DNM1L
|
dynamin 1-like
|
-3.91083
|
|
NISCH
|
nischarin
|
-3.503
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.46507
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.37287
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.30523
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-3.25013
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.2204
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.2175
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.1616
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.0958
|
|
CCDC86
|
coiled-coil domain containing 86
|
-3.08953
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.9327
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-2.85403
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.80533
|
|
TNIP1
|
TNFAIP3 interacting protein 1
|
-2.59733
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.50727
|
|
WASHC4
|
WASH complex subunit 4
|
-2.32753
|
|
LRPAP1
|
low density lipoprotein receptor-related protein associated protein 1
|
-2.25753
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.19367
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.18278
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.15725
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.12785
|
|
CCNB1
|
cyclin B1
|
-2.04953
|
