| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tretinoin 10.05 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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80 genes differentially expressed following the CRCGN013_HEPG2_24H:D03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 5.23289 |
| LOC122526780 | uncharacterized LOC122526780 | 5.02112 |
| NOSIP | nitric oxide synthase interacting protein | 4.54349 |
| HOXA5 | homeobox A5 | 4.37201 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 3.5432 |
| MYLK | myosin light chain kinase | 3.49457 |
| UBQLN2 | ubiquilin 2 | 3.32594 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.094 |
| MOK | MOK protein kinase | 2.95675 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 2.95649 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.88426 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.88323 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 2.88193 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.77975 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 2.77218 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 2.74026 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.71252 |
| CBR3 | carbonyl reductase 3 | 2.69864 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.56206 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.43251 |
| STXBP2 | syntaxin binding protein 2 | 2.42407 |
| GPATCH8 | G patch domain containing 8 | 2.3888 |
| MAP7 | microtubule-associated protein 7 | 2.35424 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | 2.29946 |
| PRR15L | proline rich 15-like | 2.29431 |
| INTS12 | integrator complex subunit 12 | 2.28337 |
| SLC9B2 | solute carrier family 9, subfamily B (NHA2, cation proton antiporter 2), member 2 | 2.23158 |
| HMOX1 | heme oxygenase 1 | 2.22134 |
| KIF20A | kinesin family member 20A | 2.20639 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.18256 |
| EVL | Enah/Vasp-like | 2.16198 |
| DDIT4 | DNA-damage-inducible transcript 4 | 2.15092 |
| CHEK2 | checkpoint kinase 2 | 2.12094 |
| PPARG | peroxisome proliferator-activated receptor gamma | 2.11197 |
| KLHDC2 | kelch domain containing 2 | 2.04661 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 2.03359 |
| PLSCR3 | phospholipid scramblase 3 | 2.01975 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | 2.01588 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 2.01303 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -6.20477 |
| LDHD | lactate dehydrogenase D | -5.93867 |
| EDN1 | endothelin 1 | -4.32114 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.16925 |
| DUSP6 | dual specificity phosphatase 6 | -4.12278 |
| INPP1 | inositol polyphosphate-1-phosphatase | -3.71134 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | -3.58474 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.55236 |
| UGDH | UDP-glucose 6-dehydrogenase | -3.44919 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.41726 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -3.33728 |
| LOC124907782 | dual specificity protein phosphatase 22 | -3.16349 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -3.05924 |
| IER3 | immediate early response 3 | -2.88377 |
| NGRN | neugrin, neurite outgrowth associated | -2.86737 |
| RAI14 | retinoic acid induced 14 | -2.84183 |
| MRPS16 | mitochondrial ribosomal protein S16 | -2.82722 |
| FAT1 | FAT atypical cadherin 1 | -2.67852 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -2.66831 |
| ZFP36 | ZFP36 ring finger protein | -2.66758 |
| GNAS | GNAS complex locus | -2.53225 |
| USP6NL | USP6 N-terminal like | -2.5175 |
| GLRX | glutaredoxin (thioltransferase) | -2.48642 |
| SNX11 | sorting nexin 11 | -2.35809 |
| GRB7 | growth factor receptor-bound protein 7 | -2.33103 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | -2.32161 |
| TRIB3 | tribbles pseudokinase 3 | -2.26389 |
| BLCAP | bladder cancer associated protein | -2.23995 |
| TXNDC9 | thioredoxin domain containing 9 | -2.23331 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.15937 |
| THAP11 | THAP domain containing 11 | -2.14652 |
| GET1 | guided entry of tail-anchored proteins factor 1 | -2.12701 |
| CMKLR2 | chemerin chemokine-like receptor 2 | -2.11753 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.10667 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -2.05954 |
| PEG10 | paternally expressed 10 | -2.04374 |
| S100A4 | S100 calcium binding protein A4 | -2.04249 |
| BRSK2 | BR serine/threonine kinase 2 | -2.03889 |
| TRIB1 | tribbles pseudokinase 1 | -2.01991 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.01889 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | -2.00633 |
