| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | tretinoin 2.51 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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69 genes differentially expressed following the CRCGN013_HEPG2_24H:D05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 8.44935 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 6.48391 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.2518 |
| HOXA5 | homeobox A5 | 4.18264 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | 3.81727 |
| HMOX1 | heme oxygenase 1 | 3.70322 |
| MAMLD1 | mastermind-like domain containing 1 | 3.49172 |
| ADGRE5 | adhesion G protein-coupled receptor E5 | 3.40024 |
| PARP2 | poly (ADP-ribose) polymerase 2 | 3.22294 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 3.1036 |
| E2F2 | E2F transcription factor 2 | 2.90806 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.88455 |
| STK10 | serine/threonine kinase 10 | 2.7929 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 2.78877 |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 | 2.56069 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.52815 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | 2.51849 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 2.51787 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.49809 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal | 2.4871 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 2.46373 |
| SMARCD2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 | 2.44061 |
| NFIL3 | nuclear factor, interleukin 3 regulated | 2.41532 |
| RAB21 | RAB21, member RAS oncogene family | 2.29243 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 2.22252 |
| WFS1 | Wolfram syndrome 1 (wolframin) | 2.20687 |
| DDIT4 | DNA-damage-inducible transcript 4 | 2.18245 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.1312 |
| IFT52 | intraflagellar transport 52 | 2.09605 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 2.07435 |
| APOC1 | apolipoprotein C-I | 2.06865 |
| MCM3 | minichromosome maintenance complex component 3 | 2.05561 |
| KLHDC2 | kelch domain containing 2 | 2.02573 |
| ZNF318 | zinc finger protein 318 | 2.00019 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DUSP6 | dual specificity phosphatase 6 | -4.55387 |
| CAB39 | calcium binding protein 39 | -4.04894 |
| ZNF586 | zinc finger protein 586 | -3.68844 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 | -3.64678 |
| INPP1 | inositol polyphosphate-1-phosphatase | -3.58517 |
| PLK1 | polo-like kinase 1 | -3.40057 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.37469 |
| IER3 | immediate early response 3 | -3.30937 |
| MVP | major vault protein | -3.25123 |
| SLC35F2 | solute carrier family 35, member F2 | -3.09111 |
| S100A4 | S100 calcium binding protein A4 | -2.96305 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -2.91501 |
| GLRX | glutaredoxin (thioltransferase) | -2.77765 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.7312 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | -2.7225 |
| CHEK1 | checkpoint kinase 1 | -2.67925 |
| CDC20 | cell division cycle 20 | -2.52754 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.48064 |
| EDN1 | endothelin 1 | -2.29952 |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) | -2.26577 |
| FAT1 | FAT atypical cadherin 1 | -2.26215 |
| SPAG4 | sperm associated antigen 4 | -2.25159 |
| USP6NL | USP6 N-terminal like | -2.24565 |
| REEP5 | receptor accessory protein 5 | -2.24248 |
| PDHX | pyruvate dehydrogenase complex, component X | -2.20375 |
| TUBB6 | tubulin, beta 6 class V | -2.19171 |
| GNAS | GNAS complex locus | -2.17762 |
| RPS5 | ribosomal protein S5 | -2.15081 |
| RAI14 | retinoic acid induced 14 | -2.13254 |
| UGDH | UDP-glucose 6-dehydrogenase | -2.12885 |
| BOP1 | block of proliferation 1 | -2.12334 |
| TLCD3A | TLC domain containing 3A | -2.11616 |
| VDAC1 | voltage-dependent anion channel 1 | -2.10048 |
| DSG2 | desmoglein 2 | -2.08954 |
| SLC19A2 | solute carrier family 19 (thiamine transporter), member 2 | -2.01428 |
