| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | 2-chloro-p-phenylenediamine sulfate 5.0 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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66 genes differentially expressed following the CRCGN013_HEPG2_24H:D10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STAP2 | signal transducing adaptor family member 2 | 4.29132 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | 4.22597 |
| MYLK | myosin light chain kinase | 4.06844 |
| AXIN1 | axin 1 | 3.83942 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 3.67291 |
| ABCB6 | ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) | 3.67119 |
| UGDH | UDP-glucose 6-dehydrogenase | 3.64982 |
| RPP38 | ribonuclease P/MRP 38kDa subunit | 3.54256 |
| CBR3 | carbonyl reductase 3 | 3.44254 |
| UBQLN2 | ubiquilin 2 | 3.43006 |
| KLHL21 | kelch-like family member 21 | 3.38901 |
| MOK | MOK protein kinase | 3.3749 |
| BZW2 | basic leucine zipper and W2 domains 2 | 3.33644 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 3.14466 |
| PPARG | peroxisome proliferator-activated receptor gamma | 3.13067 |
| TXNRD1 | thioredoxin reductase 1 | 3.12288 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 2.96739 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 2.95199 |
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 2.84428 |
| RRAGA | Ras-related GTP binding A | 2.63029 |
| MINDY1 | MINDY lysine 48 deubiquitinase 1 | 2.58833 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 2.5774 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 2.54283 |
| GATA3 | GATA binding protein 3 | 2.51808 |
| CTTN | cortactin | 2.48781 |
| LCN2 | lipocalin 2 | 2.39734 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.38983 |
| CBR1 | carbonyl reductase 1 | 2.32694 |
| CHN1 | chimerin 1 | 2.13594 |
| TATDN2 | TatD DNase domain containing 2 | 2.10868 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 2.09775 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 | 2.06757 |
| GFOD1 | glucose-fructose oxidoreductase domain containing 1 | 2.06472 |
| HMOX1 | heme oxygenase 1 | 2.03125 |
| EVL | Enah/Vasp-like | 2.00081 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CDC20 | cell division cycle 20 | -6.7315 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.77296 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -3.74204 |
| PEG10 | paternally expressed 10 | -3.59276 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.32177 |
| ZNF586 | zinc finger protein 586 | -3.26873 |
| EIF5 | eukaryotic translation initiation factor 5 | -3.13546 |
| NISCH | nischarin | -2.97843 |
| NRIP1 | nuclear receptor interacting protein 1 | -2.81885 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.6416 |
| FOSL1 | FOS-like antigen 1 | -2.55792 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -2.52192 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.50291 |
| EGF | epidermal growth factor | -2.43484 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -2.41396 |
| S100A4 | S100 calcium binding protein A4 | -2.39811 |
| SMNDC1 | survival motor neuron domain containing 1 | -2.39146 |
| CCNB2 | cyclin B2 | -2.37176 |
| MAPK13 | mitogen-activated protein kinase 13 | -2.3576 |
| NUP85 | nucleoporin 85kDa | -2.28062 |
| USP6NL | USP6 N-terminal like | -2.27611 |
| PRPF4 | pre-mRNA processing factor 4 | -2.25931 |
| PRPF39 | pre-mRNA processing factor 39 | -2.25217 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -2.18651 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -2.14856 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | -2.14159 |
| TOGARAM1 | TOG array regulator of axonemal microtubules 1 | -2.07595 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -2.07211 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | -2.02896 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -2.00547 |
| TXNIP | thioredoxin interacting protein | -2.00112 |
