CRCGN013_HEPG2_24H:D12 Gene Set
Genes
48 genes differentially expressed following the CRCGN013_HEPG2_24H:D12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
5.95302
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
5.20153
|
|
RPL39L
|
ribosomal protein L39-like
|
4.60042
|
|
E2F2
|
E2F transcription factor 2
|
4.01716
|
|
JADE2
|
jade family PHD finger 2
|
3.6771
|
|
KLHL9
|
kelch-like family member 9
|
3.64152
|
|
RAB21
|
RAB21, member RAS oncogene family
|
3.29983
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.89679
|
|
CASP2
|
caspase 2, apoptosis-related cysteine peptidase
|
2.82753
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.74281
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.65141
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
2.48749
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.45076
|
|
PRR15L
|
proline rich 15-like
|
2.41115
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.41113
|
|
EGF
|
epidermal growth factor
|
2.23397
|
|
CHEK2
|
checkpoint kinase 2
|
2.22626
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.2163
|
|
SSR3
|
signal sequence receptor, gamma (translocon-associated protein gamma)
|
2.15501
|
|
VGLL4
|
vestigial-like family member 4
|
2.14106
|
|
HMOX1
|
heme oxygenase 1
|
2.12586
|
|
PXMP2
|
peroxisomal membrane protein 2, 22kDa
|
2.08893
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.06156
|
|
LOC105379278
|
uncharacterized LOC105379278
|
2.0554
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
2.04207
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.01447
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
TLCD3A
|
TLC domain containing 3A
|
-5.92638
|
|
PCNA
|
proliferating cell nuclear antigen
|
-5.44499
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.06628
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.94806
|
|
LDHD
|
lactate dehydrogenase D
|
-3.65448
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.56655
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.39681
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-3.31588
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.30487
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-3.01571
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.65669
|
|
THAP11
|
THAP domain containing 11
|
-2.55017
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.51105
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.45255
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-2.35198
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.29951
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-2.23298
|
|
CPSF4
|
cleavage and polyadenylation specific factor 4, 30kDa
|
-2.2176
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.17482
|
|
TMEM184B
|
transmembrane protein 184B
|
-2.05972
|
|
CCNB1
|
cyclin B1
|
-2.02151
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.00565
|
