CRCGN013_HEPG2_24H:D13 Gene Set
Genes
48 genes differentially expressed following the CRCGN013_HEPG2_24H:D13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
8.73842
|
|
NOTCH1
|
notch 1
|
4.62035
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.58162
|
|
STIMATE
|
STIM activating enhancer
|
4.23189
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.97655
|
|
SFTPB
|
surfactant protein B
|
3.88157
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.79156
|
|
TBP
|
TATA box binding protein
|
3.7909
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.66155
|
|
STAP2
|
signal transducing adaptor family member 2
|
3.37259
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.238
|
|
SIRT3
|
sirtuin 3
|
3.2037
|
|
PIP4K2B
|
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
|
2.97925
|
|
PLSCR1
|
phospholipid scramblase 1
|
2.97919
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.94734
|
|
STXBP2
|
syntaxin binding protein 2
|
2.94269
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.81593
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.60936
|
|
H1-0
|
H1.0 linker histone
|
2.57445
|
|
VGLL4
|
vestigial-like family member 4
|
2.55346
|
|
GPATCH8
|
G patch domain containing 8
|
2.46874
|
|
JADE2
|
jade family PHD finger 2
|
2.35592
|
|
DOC2B
|
double C2-like domains, beta
|
2.06701
|
|
EFCAB14
|
EF-hand calcium binding domain 14
|
2.04491
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-4.82257
|
|
DSG2
|
desmoglein 2
|
-4.74256
|
|
TSPAN4
|
tetraspanin 4
|
-4.6955
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.40714
|
|
CCNB1
|
cyclin B1
|
-4.22783
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.11381
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.98345
|
|
ADI1
|
acireductone dioxygenase 1
|
-3.92939
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.83912
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.68565
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.67793
|
|
YME1L1
|
YME1-like 1 ATPase
|
-3.19231
|
|
TES
|
testin LIM domain protein
|
-2.68699
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.66676
|
|
RAB20
|
RAB20, member RAS oncogene family
|
-2.60207
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.40672
|
|
GET1
|
guided entry of tail-anchored proteins factor 1
|
-2.31154
|
|
NVL
|
nuclear VCP-like
|
-2.28317
|
|
FAT4
|
FAT atypical cadherin 4
|
-2.19626
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.1757
|
|
CSF3
|
colony stimulating factor 3 (granulocyte)
|
-2.15017
|
|
CAB39
|
calcium binding protein 39
|
-2.0878
|
|
ASAH1
|
N-acylsphingosine amidohydrolase (acid ceramidase) 1
|
-2.04633
|
|
EXT1
|
exostosin glycosyltransferase 1
|
-2.02324
|
