| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | dimethyl terephthalate 20.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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68 genes differentially expressed following the CRCGN013_HEPG2_24H:D14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.86767 |
| UBQLN2 | ubiquilin 2 | 4.82615 |
| CHMP6 | charged multivesicular body protein 6 | 4.65862 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 4.6377 |
| ABHD6 | abhydrolase domain containing 6 | 4.3958 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 4.30098 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.30006 |
| TBP | TATA box binding protein | 4.19349 |
| SOCS2 | suppressor of cytokine signaling 2 | 3.94043 |
| HOXA10 | homeobox A10 | 3.83228 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.65203 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.58563 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 3.23559 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 3.14593 |
| NOL3 | nucleolar protein 3 (apoptosis repressor with CARD domain) | 2.97529 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 2.79882 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.78725 |
| CCNF | cyclin F | 2.78195 |
| JADE2 | jade family PHD finger 2 | 2.7633 |
| HOXA10-HOXA9 | HOXA10-HOXA9 readthrough | 2.47765 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 | 2.38449 |
| ECHDC1 | ethylmalonyl-CoA decarboxylase 1 | 2.22309 |
| NHERF4 | NHERF family PDZ scaffold protein 4 | 2.21857 |
| KIF18B | kinesin family member 18B | 2.18507 |
| KIF20A | kinesin family member 20A | 2.12662 |
| IL18RAP | interleukin 18 receptor accessory protein | 2.10345 |
| PRR7 | proline rich 7 (synaptic) | 2.06135 |
| LDAH | lipid droplet associated hydrolase | 2.05741 |
| CA2 | carbonic anhydrase II | 2.04324 |
| LRRN2 | leucine rich repeat neuronal 2 | 2.03891 |
| DIO3 | deiodinase, iodothyronine, type III | 2.01221 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GNAS | GNAS complex locus | -7.62661 |
| HMG20B | high mobility group 20B | -6.10474 |
| GDF15 | growth differentiation factor 15 | -5.57439 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase | -5.13848 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.84752 |
| LDHD | lactate dehydrogenase D | -4.77922 |
| CCNB1 | cyclin B1 | -4.25831 |
| PCNA | proliferating cell nuclear antigen | -4.07655 |
| CCNB2 | cyclin B2 | -3.96167 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | -3.94671 |
| NUP85 | nucleoporin 85kDa | -3.59985 |
| CCP110 | centriolar coiled coil protein 110kDa | -3.09529 |
| ZNF586 | zinc finger protein 586 | -3.04838 |
| LNX1 | ligand of numb-protein X 1, E3 ubiquitin protein ligase | -2.85052 |
| MVP | major vault protein | -2.75243 |
| PRPF4 | pre-mRNA processing factor 4 | -2.73779 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -2.73417 |
| PPP1R9A | protein phosphatase 1, regulatory subunit 9A | -2.4796 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -2.45272 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.44368 |
| TJP2 | tight junction protein 2 | -2.39403 |
| MAP9 | microtubule-associated protein 9 | -2.38824 |
| SAP30BP | SAP30 binding protein | -2.33022 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.2808 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -2.24337 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.16738 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -2.14812 |
| TLR4 | toll-like receptor 4 | -2.14569 |
| VIM | vimentin | -2.14403 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -2.12 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.09257 |
| NUP205 | nucleoporin 205kDa | -2.07099 |
| TMEM35A | transmembrane protein 35A | -2.06332 |
| SENP7 | SUMO1/sentrin specific peptidase 7 | -2.05962 |
| STX18 | syntaxin 18 | -2.04789 |
| FAM50A | family with sequence similarity 50, member A | -2.03899 |
| C5 | complement component 5 | -2.03548 |
