CRCGN013_HEPG2_24H:D18 Gene Set
Genes
41 genes differentially expressed following the CRCGN013_HEPG2_24H:D18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
6.66815
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.11561
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.74798
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
3.09343
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.03137
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
3.00025
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.81858
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.78079
|
|
MAP7
|
microtubule-associated protein 7
|
2.72006
|
|
STXBP2
|
syntaxin binding protein 2
|
2.65053
|
|
PRKCH
|
protein kinase C, eta
|
2.61981
|
|
MMP1
|
matrix metallopeptidase 1
|
2.55401
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.54045
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.50685
|
|
CBR3
|
carbonyl reductase 3
|
2.48012
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.3985
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.31762
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.30937
|
|
LOC122526780
|
uncharacterized LOC122526780
|
2.22995
|
|
SNUPN
|
snurportin 1
|
2.16405
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.06848
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-7.24985
|
|
CCDC86
|
coiled-coil domain containing 86
|
-4.08926
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.01178
|
|
LDHD
|
lactate dehydrogenase D
|
-3.4063
|
|
MRPS2
|
mitochondrial ribosomal protein S2
|
-3.3368
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.28668
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-3.25588
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.1594
|
|
EGF
|
epidermal growth factor
|
-2.99322
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
-2.9069
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-2.70531
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.705
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.67092
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-2.41365
|
|
PPP1R26
|
protein phosphatase 1, regulatory subunit 26
|
-2.41335
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.3419
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.20752
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.17008
|
|
WDR13
|
WD repeat domain 13
|
-2.102
|
|
NVL
|
nuclear VCP-like
|
-2.0472
|
