CRCGN013_HEPG2_24H:D19 Gene Set
Genes
51 genes differentially expressed following the CRCGN013_HEPG2_24H:D19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
5.77081
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
4.20873
|
|
CHN1
|
chimerin 1
|
4.14733
|
|
GFOD1
|
glucose-fructose oxidoreductase domain containing 1
|
4.04225
|
|
MAMLD1
|
mastermind-like domain containing 1
|
4.02474
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
3.84011
|
|
SIRT3
|
sirtuin 3
|
3.56238
|
|
PEX11A
|
peroxisomal biogenesis factor 11 alpha
|
3.51495
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.31695
|
|
GRWD1
|
glutamate-rich WD repeat containing 1
|
2.84892
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.81738
|
|
PLS1
|
plastin 1
|
2.77896
|
|
NOTCH1
|
notch 1
|
2.67961
|
|
MOK
|
MOK protein kinase
|
2.65009
|
|
DNAJB2
|
DnaJ (Hsp40) homolog, subfamily B, member 2
|
2.63757
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.47993
|
|
STK10
|
serine/threonine kinase 10
|
2.42318
|
|
FPGS
|
folylpolyglutamate synthase
|
2.38952
|
|
CEP57
|
centrosomal protein 57kDa
|
2.25694
|
|
ZNF589
|
zinc finger protein 589
|
2.17815
|
|
MAST2
|
microtubule associated serine/threonine kinase 2
|
2.15434
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.12649
|
|
EPHA3
|
EPH receptor A3
|
2.09288
|
|
CCDC85B
|
coiled-coil domain containing 85B
|
2.07925
|
|
EXOSC4
|
exosome component 4
|
2.07067
|
|
EGF
|
epidermal growth factor
|
2.03809
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-6.83728
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.22919
|
|
GNAS
|
GNAS complex locus
|
-4.15315
|
|
VAT1
|
vesicle amine transport 1
|
-3.57109
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-3.2966
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.12047
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-3.04359
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.02728
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.90051
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.84381
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.74565
|
|
ZNF134
|
zinc finger protein 134
|
-2.71118
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-2.67062
|
|
CDC20
|
cell division cycle 20
|
-2.66076
|
|
PTPRK
|
protein tyrosine phosphatase, receptor type, K
|
-2.62375
|
|
RNF167
|
ring finger protein 167
|
-2.59648
|
|
TLR4
|
toll-like receptor 4
|
-2.49889
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.49769
|
|
TCERG1
|
transcription elongation regulator 1
|
-2.46233
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.33009
|
|
CCDC86
|
coiled-coil domain containing 86
|
-2.17662
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.15176
|
|
FOXN2
|
forkhead box N2
|
-2.09284
|
|
HMG20B
|
high mobility group 20B
|
-2.05226
|
|
HEBP2
|
heme binding protein 2
|
-2.02855
|
