CRCGN013_HEPG2_24H:D22 Gene Set
Genes
33 genes differentially expressed following the CRCGN013_HEPG2_24H:D22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.13807
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.07409
|
|
E2F2
|
E2F transcription factor 2
|
4.96518
|
|
NR3C1
|
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
|
4.68975
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
3.61025
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
3.59132
|
|
TBPL1
|
TBP-like 1
|
3.40281
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.11103
|
|
MCM3
|
minichromosome maintenance complex component 3
|
3.07642
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.03917
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
3.03161
|
|
CCNH
|
cyclin H
|
2.90474
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
2.88028
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.73286
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
2.72018
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.27068
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
2.23309
|
|
LCN2
|
lipocalin 2
|
2.22615
|
|
PDSS1
|
prenyl (decaprenyl) diphosphate synthase, subunit 1
|
2.14557
|
|
SQOR
|
sulfide quinone oxidoreductase
|
2.11185
|
|
TMEM11
|
transmembrane protein 11
|
2.07362
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.02196
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-7.71119
|
|
GNAS
|
GNAS complex locus
|
-7.46907
|
|
LDHD
|
lactate dehydrogenase D
|
-7.05104
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-6.48785
|
|
TLE1
|
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
|
-3.48598
|
|
CDC20
|
cell division cycle 20
|
-2.58874
|
|
CCNB1
|
cyclin B1
|
-2.58111
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.23576
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.10969
|
|
ABCF1
|
ATP-binding cassette, sub-family F (GCN20), member 1
|
-2.08114
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.07372
|
