CRCGN013_HEPG2_24H:D23 Gene Set
Genes
48 genes differentially expressed following the CRCGN013_HEPG2_24H:D23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CHN1
|
chimerin 1
|
5.79099
|
|
LAGE3
|
L antigen family, member 3
|
5.00203
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
4.51157
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.40632
|
|
STIMATE
|
STIM activating enhancer
|
4.36585
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.20832
|
|
UBQLN2
|
ubiquilin 2
|
4.0594
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
3.95941
|
|
ATP11B
|
ATPase, class VI, type 11B
|
3.88388
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.29771
|
|
GATA2
|
GATA binding protein 2
|
3.12243
|
|
PMM2
|
phosphomannomutase 2
|
2.93757
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.92785
|
|
CLPX
|
caseinolytic mitochondrial matrix peptidase chaperone subunit
|
2.89313
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.82451
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.70972
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.62558
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.61163
|
|
CYCS
|
cytochrome c, somatic
|
2.61093
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
2.55692
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.45201
|
|
SIRT3
|
sirtuin 3
|
2.3866
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
2.27225
|
|
APRT
|
adenine phosphoribosyltransferase
|
2.16791
|
|
GPATCH8
|
G patch domain containing 8
|
2.12192
|
|
ANTKMT
|
adenine nucleotide translocase lysine methyltransferase
|
2.01806
|
|
ZNF589
|
zinc finger protein 589
|
2.01008
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
NRIP1
|
nuclear receptor interacting protein 1
|
-5.31674
|
|
LDHD
|
lactate dehydrogenase D
|
-4.8027
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-4.66898
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.06897
|
|
GDF15
|
growth differentiation factor 15
|
-3.76975
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.61505
|
|
ZNF586
|
zinc finger protein 586
|
-3.43063
|
|
EGF
|
epidermal growth factor
|
-3.35317
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.24012
|
|
GNAS
|
GNAS complex locus
|
-2.92788
|
|
CCNB2
|
cyclin B2
|
-2.78221
|
|
PYGL
|
phosphorylase, glycogen, liver
|
-2.44856
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.43394
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.29493
|
|
USP36
|
ubiquitin specific peptidase 36
|
-2.26875
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.24512
|
|
FDFT1
|
farnesyl-diphosphate farnesyltransferase 1
|
-2.10505
|
|
SLC16A6
|
solute carrier family 16, member 6
|
-2.09739
|
|
NR4A2
|
nuclear receptor subfamily 4, group A, member 2
|
-2.09458
|
|
EMX2
|
empty spiracles homeobox 2
|
-2.0408
|
|
TEX30
|
testis expressed 30
|
-2.0127
|
