CRCGN013_HEPG2_24H:E01 Gene Set
Genes
55 genes differentially expressed following the CRCGN013_HEPG2_24H:E01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NOTCH1
|
notch 1
|
4.57458
|
|
RPL39L
|
ribosomal protein L39-like
|
4.43556
|
|
LCN2
|
lipocalin 2
|
4.38879
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.3868
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.29698
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
4.15149
|
|
NR1H2
|
nuclear receptor subfamily 1, group H, member 2
|
3.68936
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.50523
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
3.37682
|
|
ABHD6
|
abhydrolase domain containing 6
|
3.34255
|
|
CHN1
|
chimerin 1
|
3.29695
|
|
PLS1
|
plastin 1
|
3.2741
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.7326
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
2.66347
|
|
SULF1
|
sulfatase 1
|
2.65134
|
|
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4
|
2.62769
|
|
CDC45
|
cell division cycle 45
|
2.5326
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.5027
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.45601
|
|
FCHO1
|
FCH domain only 1
|
2.40509
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.30617
|
|
GPATCH8
|
G patch domain containing 8
|
2.25726
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.25147
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.24149
|
|
BTK
|
Bruton agammaglobulinemia tyrosine kinase
|
2.23985
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.22507
|
|
BZW2
|
basic leucine zipper and W2 domains 2
|
2.21038
|
|
FGL2
|
fibrinogen-like 2
|
2.08062
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
LDHD
|
lactate dehydrogenase D
|
-10.0
|
|
GNAS
|
GNAS complex locus
|
-6.50243
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-4.34683
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.21975
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.98489
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.6557
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.39357
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.11529
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-3.00297
|
|
WASHC4
|
WASH complex subunit 4
|
-2.98955
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.93715
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.87787
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.71338
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-2.58864
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.53376
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.43127
|
|
S100A4
|
S100 calcium binding protein A4
|
-2.32496
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.3222
|
|
CMTR1
|
cap methyltransferase 1
|
-2.13054
|
|
TOMM34
|
translocase of outer mitochondrial membrane 34
|
-2.1202
|
|
STAT1
|
signal transducer and activator of transcription 1, 91kDa
|
-2.1114
|
|
DPM1
|
dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit
|
-2.09198
|
|
ADGRL3
|
adhesion G protein-coupled receptor L3
|
-2.0521
|
|
TMOD1
|
tropomodulin 1
|
-2.01598
|
|
MVP
|
major vault protein
|
-2.0079
|
|
UBA52
|
ubiquitin A-52 residue ribosomal protein fusion product 1
|
-2.00334
|
|
DXO
|
decapping exoribonuclease
|
-2.00176
|
