CRCGN013_HEPG2_24H:E02 Gene Set
Genes
47 genes differentially expressed following the CRCGN013_HEPG2_24H:E02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
6.7022
|
|
CHN1
|
chimerin 1
|
5.31183
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.34859
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
3.73961
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.5383
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
3.48866
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.34067
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
3.25299
|
|
DNMT3A
|
DNA (cytosine-5-)-methyltransferase 3 alpha
|
2.76704
|
|
TENT4A
|
terminal nucleotidyltransferase 4A
|
2.68191
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.66845
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.58808
|
|
USP7
|
ubiquitin specific peptidase 7 (herpes virus-associated)
|
2.55637
|
|
PLP2
|
proteolipid protein 2 (colonic epithelium-enriched)
|
2.47026
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.38948
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.36629
|
|
SLC27A3
|
solute carrier family 27 (fatty acid transporter), member 3
|
2.15623
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.13163
|
|
MMP2
|
matrix metallopeptidase 2
|
2.07009
|
|
GPATCH8
|
G patch domain containing 8
|
2.05618
|
|
NOC2L
|
nucleolar complex associated 2 homolog (S. cerevisiae)
|
2.04015
|
|
RNF40
|
ring finger protein 40, E3 ubiquitin protein ligase
|
2.0173
|
|
EED
|
embryonic ectoderm development
|
2.00711
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC35F2
|
solute carrier family 35, member F2
|
-6.07812
|
|
GNAS
|
GNAS complex locus
|
-4.59356
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-4.23521
|
|
CAB39
|
calcium binding protein 39
|
-4.23515
|
|
NCK1
|
NCK adaptor protein 1
|
-4.16744
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.797
|
|
FBXO7
|
F-box protein 7
|
-3.67193
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.6618
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.59821
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.22917
|
|
FGFR4
|
fibroblast growth factor receptor 4
|
-3.02422
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-3.01663
|
|
TLR4
|
toll-like receptor 4
|
-2.80079
|
|
ZMIZ1
|
zinc finger, MIZ-type containing 1
|
-2.65722
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.631
|
|
DCK
|
deoxycytidine kinase
|
-2.30797
|
|
APOE
|
apolipoprotein E
|
-2.27033
|
|
MAP7
|
microtubule-associated protein 7
|
-2.22537
|
|
OMG
|
oligodendrocyte myelin glycoprotein
|
-2.20343
|
|
LDHD
|
lactate dehydrogenase D
|
-2.18868
|
|
SCAND1
|
SCAN domain containing 1
|
-2.18216
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.14126
|
|
RSPH14
|
radial spoke head 14 homolog (Chlamydomonas)
|
-2.08736
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.01254
|
