CRCGN013_HEPG2_24H:E03 Gene Set
Genes
47 genes differentially expressed following the CRCGN013_HEPG2_24H:E03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
7.72439
|
|
CBR3
|
carbonyl reductase 3
|
7.40375
|
|
UBQLN2
|
ubiquilin 2
|
6.63029
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.77924
|
|
CHN1
|
chimerin 1
|
4.53837
|
|
ATP11B
|
ATPase, class VI, type 11B
|
4.26299
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.23065
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
4.22719
|
|
BPHL
|
biphenyl hydrolase-like (serine hydrolase)
|
4.2195
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
4.05325
|
|
JADE2
|
jade family PHD finger 2
|
4.03983
|
|
EVL
|
Enah/Vasp-like
|
3.75906
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.68119
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.42121
|
|
GATA3
|
GATA binding protein 3
|
3.31641
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.27154
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
3.22262
|
|
ZFP36
|
ZFP36 ring finger protein
|
2.90518
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
2.6748
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
2.58776
|
|
EGF
|
epidermal growth factor
|
2.55419
|
|
RAB11FIP1
|
RAB11 family interacting protein 1 (class I)
|
2.45221
|
|
GPATCH8
|
G patch domain containing 8
|
2.37925
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
2.36069
|
|
CYCS
|
cytochrome c, somatic
|
2.31627
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.24428
|
|
RRAGA
|
Ras-related GTP binding A
|
2.21832
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
2.15054
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
2.13798
|
|
PGPEP1
|
pyroglutamyl-peptidase I
|
2.05764
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
DERA
|
deoxyribose-phosphate aldolase (putative)
|
-5.21933
|
|
CCNB2
|
cyclin B2
|
-4.35467
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.22398
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-4.11484
|
|
CDC20
|
cell division cycle 20
|
-3.98775
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.79483
|
|
CD320
|
CD320 molecule
|
-3.61159
|
|
LDHD
|
lactate dehydrogenase D
|
-3.28019
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.15835
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.74665
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.56244
|
|
PDZD2
|
PDZ domain containing 2
|
-2.54975
|
|
VAT1
|
vesicle amine transport 1
|
-2.40067
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.29094
|
|
TXNRD1
|
thioredoxin reductase 1
|
-2.26656
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.15984
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-2.14465
|
