CRCGN013_HEPG2_24H:E04 Gene Set
Genes
56 genes differentially expressed following the CRCGN013_HEPG2_24H:E04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
5.0
|
|
GPATCH8
|
G patch domain containing 8
|
4.2927
|
|
GATA3
|
GATA binding protein 3
|
3.97182
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.5852
|
|
SCRN1
|
secernin 1
|
3.41111
|
|
INPP4B
|
inositol polyphosphate-4-phosphatase, type II, 105kDa
|
2.94776
|
|
ATP11B
|
ATPase, class VI, type 11B
|
2.89069
|
|
PRKCH
|
protein kinase C, eta
|
2.80723
|
|
SULF1
|
sulfatase 1
|
2.61553
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.47793
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.42625
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.40461
|
|
CCNF
|
cyclin F
|
2.37969
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.36411
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.25068
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.19152
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.17781
|
|
DDHD2
|
DDHD domain containing 2
|
2.15772
|
|
CDK2AP1
|
cyclin-dependent kinase 2 associated protein 1
|
2.12693
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.12632
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
2.08896
|
|
RFNG
|
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
|
2.07518
|
|
FOS
|
FBJ murine osteosarcoma viral oncogene homolog
|
2.06206
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.05063
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.03781
|
|
DIPK1A
|
divergent protein kinase domain 1A
|
2.00357
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-7.28899
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-5.12563
|
|
FASTKD5
|
FAST kinase domains 5
|
-5.12393
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-4.94789
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-4.94627
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-4.92666
|
|
CAB39
|
calcium binding protein 39
|
-4.77422
|
|
NUP85
|
nucleoporin 85kDa
|
-4.45778
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.03427
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.66296
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
-3.06926
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-2.81836
|
|
MRPS7
|
mitochondrial ribosomal protein S7
|
-2.78028
|
|
RAI14
|
retinoic acid induced 14
|
-2.73659
|
|
PLK1
|
polo-like kinase 1
|
-2.72539
|
|
NT5C
|
5', 3'-nucleotidase, cytosolic
|
-2.71851
|
|
C5
|
complement component 5
|
-2.71787
|
|
JPT1
|
Jupiter microtubule associated homolog 1
|
-2.62957
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-2.62265
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.59458
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.57887
|
|
YOD1
|
YOD1 deubiquitinase
|
-2.5257
|
|
ETNK1
|
ethanolamine kinase 1
|
-2.36642
|
|
NVL
|
nuclear VCP-like
|
-2.27969
|
|
LAP3
|
leucine aminopeptidase 3
|
-2.19278
|
|
LTC4S
|
leukotriene C4 synthase
|
-2.19071
|
|
KCTD2
|
potassium channel tetramerization domain containing 2
|
-2.05064
|
|
SUMO4
|
small ubiquitin-like modifier 4
|
-2.02893
|
|
REEP1
|
receptor accessory protein 1
|
-2.01297
|
|
SQLE
|
squalene epoxidase
|
-2.00335
|
