CRCGN013_HEPG2_24H:E06 Gene Set
Genes
49 genes differentially expressed following the CRCGN013_HEPG2_24H:E06 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
4.87299
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
4.44782
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
4.40269
|
|
LCN2
|
lipocalin 2
|
3.32085
|
|
TP53
|
tumor protein p53
|
3.20527
|
|
CDC45
|
cell division cycle 45
|
3.0234
|
|
TCFL5
|
transcription factor-like 5 (basic helix-loop-helix)
|
2.83138
|
|
ANO1
|
anoctamin 1, calcium activated chloride channel
|
2.8089
|
|
CYCS
|
cytochrome c, somatic
|
2.68744
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.59475
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
2.48238
|
|
EZH2
|
enhancer of zeste 2 polycomb repressive complex 2 subunit
|
2.46528
|
|
RUVBL1
|
RuvB-like AAA ATPase 1
|
2.3377
|
|
HYOU1
|
hypoxia up-regulated 1
|
2.32391
|
|
EMSY
|
EMSY transcriptional repressor, BRCA2 interacting
|
2.29746
|
|
SDHB
|
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
|
2.25578
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
2.22633
|
|
PLEKHB1
|
pleckstrin homology domain containing, family B (evectins) member 1
|
2.20894
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
2.18554
|
|
PUF60
|
poly-U binding splicing factor 60KDa
|
2.16131
|
|
EVL
|
Enah/Vasp-like
|
2.13165
|
|
PIK3R4
|
phosphoinositide-3-kinase, regulatory subunit 4
|
2.12791
|
|
XPNPEP1
|
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
|
2.11823
|
|
CHAC1
|
ChaC glutathione-specific gamma-glutamylcyclotransferase 1
|
2.09972
|
|
SCYL3
|
SCY1-like 3 (S. cerevisiae)
|
2.09817
|
|
CHN1
|
chimerin 1
|
2.07986
|
|
PCDHB11
|
protocadherin beta 11
|
2.03779
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-6.49145
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-5.7291
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.04464
|
|
PCNA
|
proliferating cell nuclear antigen
|
-4.8921
|
|
LDHD
|
lactate dehydrogenase D
|
-4.80667
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-4.20838
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-4.01234
|
|
MAP7
|
microtubule-associated protein 7
|
-3.7459
|
|
DNAJB6
|
DnaJ (Hsp40) homolog, subfamily B, member 6
|
-3.39955
|
|
FIS1
|
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
|
-3.38837
|
|
TES
|
testin LIM domain protein
|
-3.35991
|
|
CTSD
|
cathepsin D
|
-3.25925
|
|
GADD45A
|
growth arrest and DNA-damage-inducible, alpha
|
-3.15667
|
|
NISCH
|
nischarin
|
-3.0857
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.07921
|
|
FHIP2B
|
FHF complex subunit HOOK interacting protein 2B
|
-2.46069
|
|
PRPF4
|
pre-mRNA processing factor 4
|
-2.45183
|
|
PCBD1
|
pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha
|
-2.22964
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-2.18213
|
|
EGF
|
epidermal growth factor
|
-2.09394
|
|
ZNF329
|
zinc finger protein 329
|
-2.05841
|
|
CCNB2
|
cyclin B2
|
-2.00688
|
