CRCGN013_HEPG2_24H:E07 Gene Set
Genes
51 genes differentially expressed following the CRCGN013_HEPG2_24H:E07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
5.78814
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
4.21169
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.18728
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
4.14232
|
|
LRP10
|
low density lipoprotein receptor-related protein 10
|
3.54732
|
|
MAP7
|
microtubule-associated protein 7
|
3.11099
|
|
OXCT1
|
3-oxoacid CoA transferase 1
|
3.01277
|
|
AXIN1
|
axin 1
|
2.97145
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.87111
|
|
STXBP2
|
syntaxin binding protein 2
|
2.77542
|
|
PPP1R13B
|
protein phosphatase 1, regulatory subunit 13B
|
2.72302
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.62588
|
|
AMDHD2
|
amidohydrolase domain containing 2
|
2.61657
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
2.43393
|
|
LOXL1
|
lysyl oxidase-like 1
|
2.37762
|
|
KIF23
|
kinesin family member 23
|
2.36599
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.35995
|
|
EDN1
|
endothelin 1
|
2.35884
|
|
SULF1
|
sulfatase 1
|
2.35247
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
2.30086
|
|
HJURP
|
Holliday junction recognition protein
|
2.22413
|
|
WDHD1
|
WD repeat and HMG-box DNA binding protein 1
|
2.19655
|
|
PRR15L
|
proline rich 15-like
|
2.17427
|
|
KIF20A
|
kinesin family member 20A
|
2.10597
|
|
EPHA3
|
EPH receptor A3
|
2.0906
|
|
CDC25C
|
cell division cycle 25C
|
2.08067
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.07946
|
|
SKA1
|
spindle and kinetochore associated complex subunit 1
|
2.04805
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CDC20
|
cell division cycle 20
|
-7.27388
|
|
CD320
|
CD320 molecule
|
-6.2641
|
|
GNAS
|
GNAS complex locus
|
-4.80787
|
|
LDHD
|
lactate dehydrogenase D
|
-3.89486
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-3.64256
|
|
DNAJA3
|
DnaJ (Hsp40) homolog, subfamily A, member 3
|
-3.61039
|
|
DNM1L
|
dynamin 1-like
|
-3.59582
|
|
CCP110
|
centriolar coiled coil protein 110kDa
|
-3.08605
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-3.0662
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.87284
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-2.83269
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.52017
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.51651
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.36554
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.35683
|
|
PLVAP
|
plasmalemma vesicle associated protein
|
-2.24201
|
|
MTA1
|
metastasis associated 1
|
-2.17782
|
|
SNX11
|
sorting nexin 11
|
-2.16199
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.11462
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.11344
|
|
TEX10
|
testis expressed 10
|
-2.05521
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.01447
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.01331
|
