CRCGN013_HEPG2_24H:E08 Gene Set
Genes
46 genes differentially expressed following the CRCGN013_HEPG2_24H:E08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
LCN2
|
lipocalin 2
|
6.93745
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
6.79506
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
5.12175
|
|
FCHO1
|
FCH domain only 1
|
4.41383
|
|
PHKG2
|
phosphorylase kinase, gamma 2 (testis)
|
3.66891
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.40423
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.04204
|
|
CRTAP
|
cartilage associated protein
|
2.83766
|
|
CYCS
|
cytochrome c, somatic
|
2.71972
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.69131
|
|
WDTC1
|
WD and tetratricopeptide repeats 1
|
2.35841
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
2.32579
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.30532
|
|
MAPK3
|
mitogen-activated protein kinase 3
|
2.2836
|
|
CHN1
|
chimerin 1
|
2.21396
|
|
INSIG1
|
insulin induced gene 1
|
2.12381
|
|
ARID4B
|
AT rich interactive domain 4B (RBP1-like)
|
2.10399
|
|
GPSM3
|
G-protein signaling modulator 3
|
2.04398
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-6.07353
|
|
GNAS
|
GNAS complex locus
|
-5.75969
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-4.28493
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-4.11349
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.79898
|
|
DNM1L
|
dynamin 1-like
|
-3.70762
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.69611
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-3.51412
|
|
MAP7
|
microtubule-associated protein 7
|
-3.38897
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.20532
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.95902
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.77789
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.62873
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-2.61466
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.53137
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.46976
|
|
EGF
|
epidermal growth factor
|
-2.46444
|
|
WDR7
|
WD repeat domain 7
|
-2.45778
|
|
ITGB6
|
integrin, beta 6
|
-2.27132
|
|
RASGRP3
|
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
|
-2.21927
|
|
YME1L1
|
YME1-like 1 ATPase
|
-2.14656
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-2.12419
|
|
CD83
|
CD83 molecule
|
-2.11357
|
|
PRKAA2
|
protein kinase, AMP-activated, alpha 2 catalytic subunit
|
-2.09241
|
|
POLR2M
|
polymerase (RNA) II (DNA directed) polypeptide M
|
-2.0482
|
|
CASP3
|
caspase 3, apoptosis-related cysteine peptidase
|
-2.04205
|
|
MFSD6
|
major facilitator superfamily domain containing 6
|
-2.02749
|
|
NOL4
|
nucleolar protein 4
|
-2.01547
|
