CRCGN013_HEPG2_24H:E12 Gene Set
Genes
42 genes differentially expressed following the CRCGN013_HEPG2_24H:E12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
8.47873
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
5.84837
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
5.64218
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
4.65145
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
4.23469
|
|
UBQLN2
|
ubiquilin 2
|
3.69324
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.52176
|
|
LCN2
|
lipocalin 2
|
3.48803
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.26522
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.24425
|
|
KLHL9
|
kelch-like family member 9
|
2.58582
|
|
WASF3
|
WAS protein family, member 3
|
2.56503
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.54985
|
|
MX1
|
MX dynamin-like GTPase 1
|
2.47247
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.37479
|
|
STAP2
|
signal transducing adaptor family member 2
|
2.33948
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.31003
|
|
GNA15
|
guanine nucleotide binding protein (G protein), alpha 15 (Gq class)
|
2.27379
|
|
PARP2
|
poly (ADP-ribose) polymerase 2
|
2.14805
|
|
MCUR1
|
mitochondrial calcium uniporter regulator 1
|
2.13619
|
|
HEBP1
|
heme binding protein 1
|
2.08055
|
|
EGF
|
epidermal growth factor
|
2.00312
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-5.45342
|
|
CCNB2
|
cyclin B2
|
-5.18876
|
|
TLCD3A
|
TLC domain containing 3A
|
-4.62416
|
|
FAIM
|
Fas apoptotic inhibitory molecule
|
-4.49083
|
|
DSG2
|
desmoglein 2
|
-4.2364
|
|
PLK1
|
polo-like kinase 1
|
-3.83008
|
|
LDHD
|
lactate dehydrogenase D
|
-3.80017
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.79026
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-3.47003
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.29179
|
|
RAI14
|
retinoic acid induced 14
|
-3.13268
|
|
GNAS
|
GNAS complex locus
|
-2.82488
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.77905
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-2.63752
|
|
RPS5
|
ribosomal protein S5
|
-2.35343
|
|
WFDC1
|
WAP four-disulfide core domain 1
|
-2.2928
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.11743
|
|
WDR7
|
WD repeat domain 7
|
-2.10509
|
|
CORT
|
cortistatin
|
-2.1027
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.07643
|
