CRCGN013_HEPG2_24H:E13 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description methyl (z)-2-(dimethylamino)-n-((methylcarbamoyl)oxy)-2-oxoethanimidothioate 20.07 um perturbation at 24 h in HEPG2 (Carcinogenome)
Similar Terms
Downloads & Tools

Genes

41 genes differentially expressed following the CRCGN013_HEPG2_24H:E13 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 5.17747
LCN2 lipocalin 2 4.8262
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.94829
EVL Enah/Vasp-like 3.70007
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 3.60203
E2F2 E2F transcription factor 2 3.5719
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 3.4895
MYLK myosin light chain kinase 3.48673
CYCS cytochrome c, somatic 3.2962
CARMIL1 capping protein regulator and myosin 1 linker 1 3.1424
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 2.96703
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 2.87187
DYNLT3 dynein, light chain, Tctex-type 3 2.83297
MLLT11 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 2.79923
CHMP6 charged multivesicular body protein 6 2.6839
SSBP2 single-stranded DNA binding protein 2 2.6424
CHN1 chimerin 1 2.53157
VAV3 vav 3 guanine nucleotide exchange factor 2.4988
PACSIN3 protein kinase C and casein kinase substrate in neurons 3 2.41757
KCNK1 potassium channel, two pore domain subfamily K, member 1 2.22972
CDPF1 cysteine-rich, DPF motif domain containing 1 2.18297
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 2.15253
JADE2 jade family PHD finger 2 2.11892
HSPA1A heat shock 70kDa protein 1A 2.05793

decreased expression

Symbol Name Standardized Value
GOLT1B golgi transport 1B -6.3084
MAPK13 mitogen-activated protein kinase 13 -5.19495
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -3.7025
PKIG protein kinase (cAMP-dependent, catalytic) inhibitor gamma -3.51923
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -3.33333
CCDC86 coiled-coil domain containing 86 -3.15843
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.08313
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -3.08003
PCCB propionyl CoA carboxylase, beta polypeptide -3.07127
PCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) -2.9285
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -2.9018
FASTKD5 FAST kinase domains 5 -2.7922
OXA1L oxidase (cytochrome c) assembly 1-like -2.47817
YME1L1 YME1-like 1 ATPase -2.43702
BLCAP bladder cancer associated protein -2.32523
PPP2R5E protein phosphatase 2, regulatory subunit B', epsilon isoform -2.2629
KLHL1 kelch-like family member 1 -2.03513