CRCGN013_HEPG2_24H:E14 Gene Set
Genes
41 genes differentially expressed following the CRCGN013_HEPG2_24H:E14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
7.04961
|
|
CHN1
|
chimerin 1
|
5.61358
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
4.84407
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.81353
|
|
ADAT1
|
adenosine deaminase, tRNA-specific 1
|
3.48286
|
|
EPN2
|
epsin 2
|
3.45093
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
3.2845
|
|
E2F2
|
E2F transcription factor 2
|
3.07345
|
|
UBR7
|
ubiquitin protein ligase E3 component n-recognin 7 (putative)
|
2.85717
|
|
CEP57
|
centrosomal protein 57kDa
|
2.77416
|
|
MYLK
|
myosin light chain kinase
|
2.72035
|
|
PAF1
|
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
|
2.69194
|
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
2.64143
|
|
CHMP6
|
charged multivesicular body protein 6
|
2.39062
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.31132
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.29525
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
2.29425
|
|
DEPDC1
|
DEP domain containing 1
|
2.18961
|
|
KIF20A
|
kinesin family member 20A
|
2.17421
|
|
LIFR
|
leukemia inhibitory factor receptor alpha
|
2.16723
|
|
ACTN4
|
actinin, alpha 4
|
2.08488
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
CCNB2
|
cyclin B2
|
-8.02694
|
|
LDHD
|
lactate dehydrogenase D
|
-6.7679
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-6.27394
|
|
ZNF586
|
zinc finger protein 586
|
-4.13203
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-4.06169
|
|
NGRN
|
neugrin, neurite outgrowth associated
|
-3.86895
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.83702
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-3.23066
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.69358
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.48124
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-2.40461
|
|
ZNF274
|
zinc finger protein 274
|
-2.35012
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.30074
|
|
PUM1
|
pumilio RNA-binding family member 1
|
-2.29302
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.26167
|
|
DUSP14
|
dual specificity phosphatase 14
|
-2.22906
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.17363
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.15748
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.05085
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.01866
|
