CRCGN013_HEPG2_24H:E16 Gene Set
Genes
45 genes differentially expressed following the CRCGN013_HEPG2_24H:E16 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
5.10984
|
|
LCN2
|
lipocalin 2
|
4.70291
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
4.21657
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.00624
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
3.64063
|
|
SYNE2
|
spectrin repeat containing, nuclear envelope 2
|
3.56212
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.53071
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
3.33446
|
|
NOTCH1
|
notch 1
|
3.20246
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.03851
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
2.98161
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.53606
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.5257
|
|
CASP10
|
caspase 10, apoptosis-related cysteine peptidase
|
2.49592
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.28658
|
|
CYCS
|
cytochrome c, somatic
|
2.19835
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.1935
|
|
SHB
|
Src homology 2 domain containing adaptor protein B
|
2.15738
|
|
TMEM123
|
transmembrane protein 123
|
2.09345
|
|
CLDN1
|
claudin 1
|
2.03739
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-6.88089
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
-3.77162
|
|
COG7
|
component of oligomeric golgi complex 7
|
-3.65224
|
|
SMNDC1
|
survival motor neuron domain containing 1
|
-3.57243
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-3.45426
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.367
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.275
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-3.20397
|
|
CCNB2
|
cyclin B2
|
-2.98755
|
|
TRIB3
|
tribbles pseudokinase 3
|
-2.94427
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-2.88332
|
|
ANKRD10
|
ankyrin repeat domain 10
|
-2.69298
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.4739
|
|
TLR4
|
toll-like receptor 4
|
-2.37103
|
|
LDHD
|
lactate dehydrogenase D
|
-2.35994
|
|
RNF167
|
ring finger protein 167
|
-2.27198
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.19124
|
|
FABP5
|
fatty acid binding protein 5 (psoriasis-associated)
|
-2.17045
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.15905
|
|
TPBG
|
trophoblast glycoprotein
|
-2.15101
|
|
CDC20
|
cell division cycle 20
|
-2.09977
|
|
DNTTIP2
|
deoxynucleotidyltransferase, terminal, interacting protein 2
|
-2.07565
|
|
ZNF134
|
zinc finger protein 134
|
-2.06187
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.01488
|
|
ZNF304
|
zinc finger protein 304
|
-2.01439
|
