CRCGN013_HEPG2_24H:E18 Gene Set
Genes
42 genes differentially expressed following the CRCGN013_HEPG2_24H:E18 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
7.46851
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.90074
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.85706
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.76619
|
|
ADRB2
|
adrenoceptor beta 2, surface
|
4.2641
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
3.95091
|
|
C2CD2
|
C2 calcium-dependent domain containing 2
|
3.82897
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
3.75614
|
|
CHMP6
|
charged multivesicular body protein 6
|
3.62031
|
|
CIAO3
|
cytosolic iron-sulfur assembly component 3
|
3.51557
|
|
LCN2
|
lipocalin 2
|
3.45196
|
|
CBR3
|
carbonyl reductase 3
|
3.34593
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
3.32801
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.21587
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.99434
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.82266
|
|
KCNK1
|
potassium channel, two pore domain subfamily K, member 1
|
2.53841
|
|
PDLIM1
|
PDZ and LIM domain 1
|
2.47957
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
2.12998
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.00526
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-5.06632
|
|
GNAS
|
GNAS complex locus
|
-4.50487
|
|
HAT1
|
histone acetyltransferase 1
|
-3.71578
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.60874
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-3.54837
|
|
PPP2R3C
|
protein phosphatase 2, regulatory subunit B'', gamma
|
-3.52939
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.43535
|
|
UBE3C
|
ubiquitin protein ligase E3C
|
-3.33654
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.89668
|
|
CASP7
|
caspase 7, apoptosis-related cysteine peptidase
|
-2.7553
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-2.73134
|
|
RGS2
|
regulator of G-protein signaling 2
|
-2.62577
|
|
TLR4
|
toll-like receptor 4
|
-2.58714
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.52688
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.50589
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.31234
|
|
CCNB2
|
cyclin B2
|
-2.2556
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-2.24236
|
|
LDHD
|
lactate dehydrogenase D
|
-2.22718
|
|
CNDP2
|
CNDP dipeptidase 2 (metallopeptidase M20 family)
|
-2.21829
|
|
SCAND1
|
SCAN domain containing 1
|
-2.11849
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.02073
|
