CRCGN013_HEPG2_24H:E19 Gene Set
Genes
51 genes differentially expressed following the CRCGN013_HEPG2_24H:E19 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CDPF1
|
cysteine-rich, DPF motif domain containing 1
|
6.33645
|
|
CHN1
|
chimerin 1
|
5.1446
|
|
DRAP1
|
DR1-associated protein 1 (negative cofactor 2 alpha)
|
4.80028
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
4.76564
|
|
TXNRD1
|
thioredoxin reductase 1
|
4.23282
|
|
UGDH
|
UDP-glucose 6-dehydrogenase
|
3.9107
|
|
ABHD4
|
abhydrolase domain containing 4
|
3.71759
|
|
STXBP2
|
syntaxin binding protein 2
|
3.61176
|
|
HEBP1
|
heme binding protein 1
|
3.50518
|
|
MAPKAPK5
|
mitogen-activated protein kinase-activated protein kinase 5
|
3.49605
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
3.32039
|
|
ABCB6
|
ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
|
3.23676
|
|
SLC75A1
|
solute carrier family 75 member 1
|
3.11815
|
|
MAP7
|
microtubule-associated protein 7
|
3.11015
|
|
SATB1
|
SATB homeobox 1
|
2.91735
|
|
CGRRF1
|
cell growth regulator with ring finger domain 1
|
2.85735
|
|
SCRN1
|
secernin 1
|
2.83991
|
|
PCDHB11
|
protocadherin beta 11
|
2.69668
|
|
SNAP25
|
synaptosomal-associated protein, 25kDa
|
2.63196
|
|
ST3GAL5
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
|
2.5746
|
|
PPIC
|
peptidylprolyl isomerase C (cyclophilin C)
|
2.55054
|
|
CNPY3
|
canopy FGF signaling regulator 3
|
2.37417
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.36295
|
|
PRR15L
|
proline rich 15-like
|
2.32601
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
2.2228
|
|
SQSTM1
|
sequestosome 1
|
2.1676
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.07831
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.05328
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
PCNA
|
proliferating cell nuclear antigen
|
-8.80285
|
|
LDHD
|
lactate dehydrogenase D
|
-6.50608
|
|
VAT1
|
vesicle amine transport 1
|
-5.53803
|
|
PCCB
|
propionyl CoA carboxylase, beta polypeptide
|
-4.22228
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.51155
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-3.35335
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.13767
|
|
ARID5B
|
AT rich interactive domain 5B (MRF1-like)
|
-3.06675
|
|
CHMP4B
|
charged multivesicular body protein 4B
|
-3.0328
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-3.00495
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.75769
|
|
ZW10
|
zw10 kinetochore protein
|
-2.75745
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.69544
|
|
SNRPB2
|
small nuclear ribonucleoprotein polypeptide B
|
-2.54143
|
|
USP6NL
|
USP6 N-terminal like
|
-2.42689
|
|
ESF1
|
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
|
-2.3849
|
|
DDRGK1
|
DDRGK domain containing 1
|
-2.38033
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.31975
|
|
CCNB2
|
cyclin B2
|
-2.20735
|
|
TLCD3A
|
TLC domain containing 3A
|
-2.11082
|
|
GNAS
|
GNAS complex locus
|
-2.06368
|
|
CDS2
|
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
|
-2.02057
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.01075
|
