CRCGN013_HEPG2_24H:E22 Gene Set
Genes
47 genes differentially expressed following the CRCGN013_HEPG2_24H:E22 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
SQOR
|
sulfide quinone oxidoreductase
|
4.92636
|
|
UBQLN2
|
ubiquilin 2
|
4.86093
|
|
STK10
|
serine/threonine kinase 10
|
4.44018
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.09347
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.86423
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
3.61791
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.34474
|
|
RRAGA
|
Ras-related GTP binding A
|
3.25717
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.23668
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
3.19773
|
|
CHN1
|
chimerin 1
|
3.03986
|
|
LCN2
|
lipocalin 2
|
2.98947
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.76618
|
|
SFTPB
|
surfactant protein B
|
2.7456
|
|
GARRE1
|
granule associated Rac and RHOG effector 1
|
2.68452
|
|
CCNH
|
cyclin H
|
2.50521
|
|
PLSCR3
|
phospholipid scramblase 3
|
2.4688
|
|
ABHD4
|
abhydrolase domain containing 4
|
2.42838
|
|
GPATCH8
|
G patch domain containing 8
|
2.37115
|
|
MMP1
|
matrix metallopeptidase 1
|
2.35583
|
|
MKNK1
|
MAP kinase interacting serine/threonine kinase 1
|
2.35246
|
|
DNAJC15
|
DnaJ (Hsp40) homolog, subfamily C, member 15
|
2.1073
|
|
CDC42SE1
|
CDC42 small effector 1
|
2.06346
|
|
NDEL1
|
nudE neurodevelopment protein 1-like 1
|
2.0135
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-5.85316
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.79635
|
|
GTPBP8
|
GTP-binding protein 8 (putative)
|
-4.73764
|
|
POLR2I
|
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
|
-4.06297
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.0541
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-3.98377
|
|
LDHD
|
lactate dehydrogenase D
|
-3.97254
|
|
ABL1
|
ABL proto-oncogene 1, non-receptor tyrosine kinase
|
-3.88048
|
|
RAI14
|
retinoic acid induced 14
|
-3.69222
|
|
TM9SF3
|
transmembrane 9 superfamily member 3
|
-3.22953
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.21678
|
|
TLR4
|
toll-like receptor 4
|
-3.04871
|
|
GPATCH1
|
G patch domain containing 1
|
-2.89091
|
|
SNX11
|
sorting nexin 11
|
-2.66537
|
|
CHEK1
|
checkpoint kinase 1
|
-2.49326
|
|
NRIP1
|
nuclear receptor interacting protein 1
|
-2.42421
|
|
MGAT4A
|
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
|
-2.33996
|
|
ZNF146
|
zinc finger protein 146
|
-2.22307
|
|
RPS4Y1
|
ribosomal protein S4, Y-linked 1
|
-2.21033
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-2.1707
|
|
ERCC5
|
excision repair cross-complementation group 5
|
-2.10436
|
|
LIN37
|
lin-37 DREAM MuvB core complex component
|
-2.07353
|
|
SDHAF1
|
succinate dehydrogenase complex assembly factor 1
|
-2.04364
|
