CRCGN013_HEPG2_24H:E23 Gene Set
Genes
39 genes differentially expressed following the CRCGN013_HEPG2_24H:E23 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
4.34273
|
|
CYCS
|
cytochrome c, somatic
|
4.28422
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
4.04205
|
|
DDX42
|
DEAD (Asp-Glu-Ala-Asp) box helicase 42
|
3.33752
|
|
SFTPB
|
surfactant protein B
|
3.1871
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.08132
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.99735
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
2.81869
|
|
COPS7A
|
COP9 signalosome subunit 7A
|
2.81098
|
|
RRS1
|
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
|
2.76662
|
|
NOL3
|
nucleolar protein 3 (apoptosis repressor with CARD domain)
|
2.76317
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
2.71848
|
|
EGF
|
epidermal growth factor
|
2.69722
|
|
TRIM13
|
tripartite motif containing 13
|
2.58919
|
|
PRR15L
|
proline rich 15-like
|
2.53906
|
|
MAP7
|
microtubule-associated protein 7
|
2.5223
|
|
CCNH
|
cyclin H
|
2.39464
|
|
GDF10
|
growth differentiation factor 10
|
2.36942
|
|
ZMYM2
|
zinc finger, MYM-type 2
|
2.36467
|
|
STXBP2
|
syntaxin binding protein 2
|
2.34762
|
|
PFN2
|
profilin 2
|
2.11506
|
|
NFATC4
|
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4
|
2.10441
|
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
|
2.04416
|
|
SPTAN1
|
spectrin, alpha, non-erythrocytic 1
|
2.00797
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-7.64963
|
|
LAP3
|
leucine aminopeptidase 3
|
-5.29833
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.4309
|
|
PECR
|
peroxisomal trans-2-enoyl-CoA reductase
|
-4.2848
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.54051
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.2351
|
|
CCNB2
|
cyclin B2
|
-2.93658
|
|
ZNF134
|
zinc finger protein 134
|
-2.41536
|
|
SNCA
|
synuclein, alpha (non A4 component of amyloid precursor)
|
-2.3762
|
|
HERC5
|
HECT and RLD domain containing E3 ubiquitin protein ligase 5
|
-2.33464
|
|
PDHX
|
pyruvate dehydrogenase complex, component X
|
-2.17545
|
|
YIPF5
|
Yip1 domain family, member 5
|
-2.15125
|
|
ACOT7
|
acyl-CoA thioesterase 7
|
-2.09622
|
|
GDPD5
|
glycerophosphodiester phosphodiesterase domain containing 5
|
-2.04609
|
|
TLR4
|
toll-like receptor 4
|
-2.04598
|
