CRCGN013_HEPG2_24H:E24 Gene Set
Genes
32 genes differentially expressed following the CRCGN013_HEPG2_24H:E24 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
5.5497
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
4.62361
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
4.50547
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
4.09832
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
3.92443
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.79298
|
|
ADGRE5
|
adhesion G protein-coupled receptor E5
|
3.55544
|
|
RAB31
|
RAB31, member RAS oncogene family
|
2.65663
|
|
EPHA3
|
EPH receptor A3
|
2.48521
|
|
KLHL9
|
kelch-like family member 9
|
2.43836
|
|
TIMM17B
|
translocase of inner mitochondrial membrane 17 homolog B (yeast)
|
2.43646
|
|
MMP1
|
matrix metallopeptidase 1
|
2.41083
|
|
HEXB
|
hexosaminidase B (beta polypeptide)
|
2.1628
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
2.12027
|
|
NISCH
|
nischarin
|
2.07246
|
|
GNAI1
|
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
|
2.02919
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GOLT1B
|
golgi transport 1B
|
-9.01683
|
|
PCNA
|
proliferating cell nuclear antigen
|
-9.01109
|
|
CCNB2
|
cyclin B2
|
-6.7617
|
|
LDHD
|
lactate dehydrogenase D
|
-5.17748
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-4.98628
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-4.45008
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-3.70271
|
|
TLCD3A
|
TLC domain containing 3A
|
-3.68715
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-3.33874
|
|
MAPK13
|
mitogen-activated protein kinase 13
|
-2.96554
|
|
TLR4
|
toll-like receptor 4
|
-2.31295
|
|
UTP11
|
UTP11 small subunit processome component
|
-2.25155
|
|
CRK
|
v-crk avian sarcoma virus CT10 oncogene homolog
|
-2.24844
|
|
TXNDC9
|
thioredoxin domain containing 9
|
-2.13154
|
|
MOSPD3
|
motile sperm domain containing 3
|
-2.05208
|
|
RECQL
|
RecQ helicase-like
|
-2.03439
|
