CRCGN013_HEPG2_24H:F01 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ethyl alcohol 42.4 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

39 genes differentially expressed following the CRCGN013_HEPG2_24H:F01 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
LCN2 lipocalin 2 6.23375
GPER1 G protein-coupled estrogen receptor 1 6.20399
CBR3 carbonyl reductase 3 4.64879
IKZF1 IKAROS family zinc finger 1 (Ikaros) 4.50218
PPARG peroxisome proliferator-activated receptor gamma 4.30194
HLA-DMA major histocompatibility complex, class II, DM alpha 4.10975
BACE2 beta-site APP-cleaving enzyme 2 4.08361
C2CD2 C2 calcium-dependent domain containing 2 3.98587
SNAP25 synaptosomal-associated protein, 25kDa 3.90966
TIAM1 T-cell lymphoma invasion and metastasis 1 3.36388
NOSIP nitric oxide synthase interacting protein 3.34445
MCUR1 mitochondrial calcium uniporter regulator 1 3.12448
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 3.1187
SSBP2 single-stranded DNA binding protein 2 2.69679
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 2.59778
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 2.51652
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 2.51487
CREB1 cAMP responsive element binding protein 1 2.17826
TBXA2R thromboxane A2 receptor 2.03893
FCHO1 FCH domain only 1 2.0081

decreased expression

Symbol Name Standardized Value
OXA1L oxidase (cytochrome c) assembly 1-like -4.62612
ACOT9 acyl-CoA thioesterase 9 -4.45513
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -4.28104
CDC20 cell division cycle 20 -4.18474
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -3.85136
SLC35F2 solute carrier family 35, member F2 -3.41833
TCERG1 transcription elongation regulator 1 -3.3888
RAI14 retinoic acid induced 14 -3.24254
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) -3.07473
MAPK13 mitogen-activated protein kinase 13 -3.03349
GNAS GNAS complex locus -2.83542
CCNB2 cyclin B2 -2.83353
CRK v-crk avian sarcoma virus CT10 oncogene homolog -2.38643
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 -2.36728
SNX11 sorting nexin 11 -2.28232
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A -2.25318
GRB7 growth factor receptor-bound protein 7 -2.24197
FJX1 four jointed box 1 (Drosophila) -2.14189
RGS2 regulator of G-protein signaling 2 -2.0004