| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ethyl alcohol 21.2 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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70 genes differentially expressed following the CRCGN013_HEPG2_24H:F02 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPER1 | G protein-coupled estrogen receptor 1 | 6.48562 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 6.40757 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 6.10805 |
| PNKP | polynucleotide kinase 3'-phosphatase | 5.27278 |
| GSTZ1 | glutathione S-transferase zeta 1 | 5.16165 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 4.76834 |
| NOSIP | nitric oxide synthase interacting protein | 4.69641 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.67031 |
| STK10 | serine/threonine kinase 10 | 4.53925 |
| MOK | MOK protein kinase | 4.48917 |
| BZW2 | basic leucine zipper and W2 domains 2 | 4.30542 |
| MAP7 | microtubule-associated protein 7 | 4.15121 |
| STIMATE | STIM activating enhancer | 4.13159 |
| GATA3 | GATA binding protein 3 | 3.66128 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.52174 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 3.21415 |
| CRTAP | cartilage associated protein | 3.11347 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 2.68929 |
| FPGS | folylpolyglutamate synthase | 2.57469 |
| KIF20A | kinesin family member 20A | 2.54056 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | 2.46799 |
| WDTC1 | WD and tetratricopeptide repeats 1 | 2.45078 |
| LOC122526780 | uncharacterized LOC122526780 | 2.37748 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.35592 |
| CYP2A6 | cytochrome P450, family 2, subfamily A, polypeptide 6 | 2.32217 |
| PLA2G12A | phospholipase A2, group XIIA | 2.31103 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial | 2.27166 |
| MECR | mitochondrial trans-2-enoyl-CoA reductase | 2.23144 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.17121 |
| IL23A | interleukin 23, alpha subunit p19 | 2.09495 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 2.0646 |
| E2F8 | E2F transcription factor 8 | 2.04041 |
| SRPRB | signal recognition particle receptor, B subunit | 2.02073 |
| INTS7 | integrator complex subunit 7 | 2.01709 |
| FOXC1 | forkhead box C1 | 2.00379 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DHRS7 | dehydrogenase/reductase (SDR family) member 7 | -8.38028 |
| GNAS | GNAS complex locus | -4.54864 |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 | -4.47126 |
| SLC35F2 | solute carrier family 35, member F2 | -4.32367 |
| TSPAN4 | tetraspanin 4 | -4.13808 |
| CDC20 | cell division cycle 20 | -4.11852 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -4.0911 |
| FGFR4 | fibroblast growth factor receptor 4 | -4.04529 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -3.90966 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -3.77453 |
| LDHD | lactate dehydrogenase D | -3.73312 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.63286 |
| CCNB2 | cyclin B2 | -3.47493 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.36245 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.31973 |
| CAB39 | calcium binding protein 39 | -3.18295 |
| VDAC1 | voltage-dependent anion channel 1 | -3.15075 |
| WASHC4 | WASH complex subunit 4 | -3.12121 |
| UBE3C | ubiquitin protein ligase E3C | -3.08804 |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 | -2.84506 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.75254 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.65006 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.61496 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -2.48146 |
| MUC13 | mucin 13, cell surface associated | -2.37647 |
| SCAND1 | SCAN domain containing 1 | -2.35897 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | -2.2893 |
| ITGB1BP1 | integrin beta 1 binding protein 1 | -2.21384 |
| CRNN | cornulin | -2.19171 |
| EFNA1 | ephrin-A1 | -2.18318 |
| GDPD5 | glycerophosphodiester phosphodiesterase domain containing 5 | -2.16303 |
| TXNDC9 | thioredoxin domain containing 9 | -2.15627 |
| ICAM3 | intercellular adhesion molecule 3 | -2.09637 |
| MT1H | metallothionein 1H | -2.04293 |
| SP3 | Sp3 transcription factor | -2.00602 |
