CRCGN013_HEPG2_24H:F03 Gene Set
Genes
50 genes differentially expressed following the CRCGN013_HEPG2_24H:F03 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
6.41432
|
|
MINDY1
|
MINDY lysine 48 deubiquitinase 1
|
4.21061
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
3.55806
|
|
SNX7
|
sorting nexin 7
|
3.43244
|
|
LSR
|
lipolysis stimulated lipoprotein receptor
|
3.27732
|
|
CCL2
|
chemokine (C-C motif) ligand 2
|
3.24265
|
|
PTGS2
|
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
|
3.18575
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
3.13984
|
|
BACE2
|
beta-site APP-cleaving enzyme 2
|
3.08971
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
2.88608
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
2.87161
|
|
MYLK
|
myosin light chain kinase
|
2.83033
|
|
INSIG1
|
insulin induced gene 1
|
2.62675
|
|
PNKP
|
polynucleotide kinase 3'-phosphatase
|
2.54562
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.39265
|
|
OXCT1
|
3-oxoacid CoA transferase 1
|
2.36709
|
|
ETS1
|
v-ets avian erythroblastosis virus E26 oncogene homolog 1
|
2.3453
|
|
DYRK3
|
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
|
2.3316
|
|
SH3D19
|
SH3 domain containing 19
|
2.30458
|
|
PREB
|
prolactin regulatory element binding
|
2.23745
|
|
CCNA1
|
cyclin A1
|
2.22676
|
|
HOOK2
|
hook microtubule-tethering protein 2
|
2.13145
|
|
MLLT11
|
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
|
2.10209
|
|
LPAR2
|
lysophosphatidic acid receptor 2
|
2.06878
|
|
SLC25A13
|
solute carrier family 25 (aspartate/glutamate carrier), member 13
|
2.04788
|
|
TREM1
|
triggering receptor expressed on myeloid cells 1
|
2.03837
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
GNAS
|
GNAS complex locus
|
-4.88099
|
|
RGS2
|
regulator of G-protein signaling 2
|
-4.78282
|
|
FASTKD5
|
FAST kinase domains 5
|
-4.0394
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.87471
|
|
PPP2R5E
|
protein phosphatase 2, regulatory subunit B', epsilon isoform
|
-3.86774
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-3.41065
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-3.28771
|
|
TCTN1
|
tectonic family member 1
|
-3.26438
|
|
MVP
|
major vault protein
|
-3.02149
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.99736
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.68816
|
|
HERPUD1
|
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
|
-2.65548
|
|
FIP1L1
|
factor interacting with PAPOLA and CPSF1
|
-2.61237
|
|
CCNB2
|
cyclin B2
|
-2.60839
|
|
S100A4
|
S100 calcium binding protein A4
|
-2.56464
|
|
GHR
|
growth hormone receptor
|
-2.48672
|
|
ZNF586
|
zinc finger protein 586
|
-2.4069
|
|
LAGE3
|
L antigen family, member 3
|
-2.40445
|
|
ERBB2
|
erb-b2 receptor tyrosine kinase 2
|
-2.20605
|
|
WASHC4
|
WASH complex subunit 4
|
-2.20561
|
|
RALA
|
v-ral simian leukemia viral oncogene homolog A (ras related)
|
-2.13032
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-2.11025
|
|
CAB39
|
calcium binding protein 39
|
-2.07169
|
|
TWF2
|
twinfilin actin binding protein 2
|
-2.0659
|
