CRCGN013_HEPG2_24H:F04 Gene Set

Dataset Carcinogenome Chemical Perturbation Carcinogenicity Signatures
Category transcriptomics
Type small molecule perturbation
Description ethyl alcohol 5.3 um perturbation at 24 h in HEPG2 (Carcinogenome)
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Genes

33 genes differentially expressed following the CRCGN013_HEPG2_24H:F04 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.

increased expression

Symbol Name Standardized Value
CHN1 chimerin 1 5.34897
PTPN6 protein tyrosine phosphatase, non-receptor type 6 4.45634
NFIL3 nuclear factor, interleukin 3 regulated 4.01856
LSR lipolysis stimulated lipoprotein receptor 3.40506
TBP TATA box binding protein 3.14708
STXBP2 syntaxin binding protein 2 2.75331
ISOC1 isochorismatase domain containing 1 2.48675
HYOU1 hypoxia up-regulated 1 2.25161
GPATCH8 G patch domain containing 8 2.14889
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog 2.08632

decreased expression

Symbol Name Standardized Value
LDHD lactate dehydrogenase D -5.16071
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta -4.98632
CCNB1 cyclin B1 -4.72702
MRPS2 mitochondrial ribosomal protein S2 -4.64353
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 -4.626
HSD17B11 hydroxysteroid (17-beta) dehydrogenase 11 -4.45404
IARS2 isoleucyl-tRNA synthetase 2, mitochondrial -4.28764
DNM1L dynamin 1-like -4.28232
ADI1 acireductone dioxygenase 1 -3.72687
RRP12 ribosomal RNA processing 12 homolog (S. cerevisiae) -3.03574
UBE3C ubiquitin protein ligase E3C -2.86831
MAPK13 mitogen-activated protein kinase 13 -2.85736
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D -2.81021
OXA1L oxidase (cytochrome c) assembly 1-like -2.39882
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 -2.30072
CDK5RAP2 CDK5 regulatory subunit associated protein 2 -2.2608
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.23168
CCP110 centriolar coiled coil protein 110kDa -2.22595
NRIP1 nuclear receptor interacting protein 1 -2.22571
RFC2 replication factor C (activator 1) 2, 40kDa -2.18566
PRPF4 pre-mRNA processing factor 4 -2.1682
HLA-DMA major histocompatibility complex, class II, DM alpha -2.09653
SUPV3L1 suppressor of var1, 3-like 1 (S. cerevisiae) -2.00409