| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | ethyl alcohol 2.65 um perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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52 genes differentially expressed following the CRCGN013_HEPG2_24H:F05 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 5.92028 |
| ATP11B | ATPase, class VI, type 11B | 5.06636 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.89656 |
| C2CD2 | C2 calcium-dependent domain containing 2 | 4.79581 |
| PPARG | peroxisome proliferator-activated receptor gamma | 4.61037 |
| SSBP2 | single-stranded DNA binding protein 2 | 4.59863 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 3.69599 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 3.48637 |
| ABCC5 | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 3.20599 |
| HSPA1A | heat shock 70kDa protein 1A | 3.03451 |
| MAP3K4 | mitogen-activated protein kinase kinase kinase 4 | 3.014 |
| CHMP6 | charged multivesicular body protein 6 | 2.80708 |
| MCUR1 | mitochondrial calcium uniporter regulator 1 | 2.77576 |
| ZNF318 | zinc finger protein 318 | 2.69498 |
| TESK1 | testis-specific kinase 1 | 2.66258 |
| CYCS | cytochrome c, somatic | 2.59144 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.51856 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 2.46071 |
| DIPK1A | divergent protein kinase domain 1A | 2.21537 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.20002 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.05331 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 2.0414 |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase | 2.04011 |
| COPS7A | COP9 signalosome subunit 7A | 2.03087 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -10.0 |
| GNAS | GNAS complex locus | -6.28216 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -5.25749 |
| CCNB2 | cyclin B2 | -5.06149 |
| PCNA | proliferating cell nuclear antigen | -4.31063 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -4.16942 |
| FBXL12 | F-box and leucine-rich repeat protein 12 | -3.43571 |
| KDM3A | lysine (K)-specific demethylase 3A | -3.30901 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -3.16166 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.8788 |
| HMG20B | high mobility group 20B | -2.86003 |
| TLR4 | toll-like receptor 4 | -2.59543 |
| EGF | epidermal growth factor | -2.56293 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -2.49299 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | -2.37698 |
| REEP5 | receptor accessory protein 5 | -2.28372 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -2.21655 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.18208 |
| MARCHF5 | membrane associated ring-CH-type finger 5 | -2.13953 |
| RBBP8 | retinoblastoma binding protein 8 | -2.13371 |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) | -2.1074 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -2.09316 |
| PYCR1 | pyrroline-5-carboxylate reductase 1 | -2.0726 |
| LGSN | lengsin, lens protein with glutamine synthetase domain | -2.06424 |
| YBX1 | Y box binding protein 1 | -2.06417 |
| PSME1 | proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) | -2.01458 |
| HEATR1 | HEAT repeat containing 1 | -2.01085 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | -2.00186 |
