| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
59 genes differentially expressed following the CRCGN013_HEPG2_24H:F07 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LCN2 | lipocalin 2 | 6.84145 |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 | 6.22926 |
| STIMATE | STIM activating enhancer | 6.165 |
| SSBP2 | single-stranded DNA binding protein 2 | 5.43874 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 3.85502 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 3.64166 |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) | 3.5112 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 3.25782 |
| E2F2 | E2F transcription factor 2 | 3.16793 |
| MOK | MOK protein kinase | 3.09102 |
| CYCS | cytochrome c, somatic | 2.81071 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 2.77565 |
| HSPA1A | heat shock 70kDa protein 1A | 2.65748 |
| TBP | TATA box binding protein | 2.65406 |
| ADAM10 | ADAM metallopeptidase domain 10 | 2.58471 |
| ALDOC | aldolase C, fructose-bisphosphate | 2.55054 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 2.52242 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | 2.51945 |
| PPIC | peptidylprolyl isomerase C (cyclophilin C) | 2.43789 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 2.4241 |
| CEBPD | CCAAT/enhancer binding protein (C/EBP), delta | 2.39563 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2.18881 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 2.17022 |
| LYN | LYN proto-oncogene, Src family tyrosine kinase | 2.16454 |
| UBQLN2 | ubiquilin 2 | 2.13953 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 2.13451 |
| GPATCH8 | G patch domain containing 8 | 2.11624 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 2.03495 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MAPK13 | mitogen-activated protein kinase 13 | -5.31884 |
| GNAS | GNAS complex locus | -4.89152 |
| CCNB1 | cyclin B1 | -3.89603 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -3.84683 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | -3.82184 |
| TRIB3 | tribbles pseudokinase 3 | -3.76626 |
| PLK1 | polo-like kinase 1 | -3.43392 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.40576 |
| C2CD5 | C2 calcium-dependent domain containing 5 | -3.39869 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | -3.38873 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -3.15907 |
| CNDP2 | CNDP dipeptidase 2 (metallopeptidase M20 family) | -2.98975 |
| CDC25B | cell division cycle 25B | -2.90656 |
| DERA | deoxyribose-phosphate aldolase (putative) | -2.82757 |
| PCK2 | phosphoenolpyruvate carboxykinase 2 (mitochondrial) | -2.80176 |
| EGF | epidermal growth factor | -2.76913 |
| ADI1 | acireductone dioxygenase 1 | -2.66755 |
| UBE3C | ubiquitin protein ligase E3C | -2.66614 |
| H1-5 | H1.5 linker histone, cluster member | -2.64338 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -2.58851 |
| VDAC1 | voltage-dependent anion channel 1 | -2.46957 |
| H2BC14 | H2B clustered histone 14 | -2.41515 |
| HMG20B | high mobility group 20B | -2.3735 |
| CASP7 | caspase 7, apoptosis-related cysteine peptidase | -2.27635 |
| ZNF586 | zinc finger protein 586 | -2.25212 |
| CCNK | cyclin K | -2.20808 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -2.15845 |
| GSTA1 | glutathione S-transferase alpha 1 | -2.10044 |
| FAT1 | FAT atypical cadherin 1 | -2.00764 |
| RAB27B | RAB27B, member RAS oncogene family | -2.00636 |
| HPCAL1 | hippocalcin-like 1 | -2.00618 |
