| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
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55 genes differentially expressed following the CRCGN013_HEPG2_24H:F08 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | 6.71945 |
| LOC122526780 | uncharacterized LOC122526780 | 5.28042 |
| PPARG | peroxisome proliferator-activated receptor gamma | 5.25073 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | 4.60025 |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 | 4.54296 |
| MYLK | myosin light chain kinase | 4.51455 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 4.50637 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 4.45634 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | 4.42802 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 4.31159 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 4.11337 |
| EPHB2 | EPH receptor B2 | 4.05423 |
| P4HTM | prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) | 4.00219 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.6456 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 3.26888 |
| RRAGA | Ras-related GTP binding A | 3.2068 |
| GPER1 | G protein-coupled estrogen receptor 1 | 2.87624 |
| RRS1 | RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) | 2.79952 |
| PROS1 | protein S (alpha) | 2.70838 |
| CHN1 | chimerin 1 | 2.56379 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.46597 |
| EVL | Enah/Vasp-like | 2.3818 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | 2.32497 |
| EGF | epidermal growth factor | 2.24291 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | 2.12843 |
| TAC4 | tachykinin 4 (hemokinin) | 2.08028 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TNIP1 | TNFAIP3 interacting protein 1 | -6.72279 |
| CCNB2 | cyclin B2 | -4.64844 |
| PKIG | protein kinase (cAMP-dependent, catalytic) inhibitor gamma | -4.45401 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -4.43818 |
| TRIB3 | tribbles pseudokinase 3 | -4.38626 |
| TARBP1 | TAR (HIV-1) RNA binding protein 1 | -4.1836 |
| FGFR4 | fibroblast growth factor receptor 4 | -3.56892 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | -3.30313 |
| TXNDC9 | thioredoxin domain containing 9 | -3.21331 |
| GNAS | GNAS complex locus | -3.1743 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -3.06261 |
| MAPK13 | mitogen-activated protein kinase 13 | -3.01242 |
| CAB39 | calcium binding protein 39 | -2.92758 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | -2.78087 |
| ADI1 | acireductone dioxygenase 1 | -2.6906 |
| LOC124907782 | dual specificity protein phosphatase 22 | -2.61662 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -2.49837 |
| EXT1 | exostosin glycosyltransferase 1 | -2.39524 |
| MYNN | myoneurin | -2.30035 |
| VDAC1 | voltage-dependent anion channel 1 | -2.25186 |
| BAHD1 | bromo adjacent homology domain containing 1 | -2.19998 |
| DEFA4 | defensin, alpha 4, corticostatin | -2.19779 |
| PHF21A | PHD finger protein 21A | -2.17671 |
| PPP6R1 | protein phosphatase 6, regulatory subunit 1 | -2.14975 |
| KIAA0040 | KIAA0040 | -2.05527 |
| AKAP8 | A kinase (PRKA) anchor protein 8 | -2.02547 |
| TMEM41B | transmembrane protein 41B | -2.0236 |
| DEFA3 | defensin, alpha 3, neutrophil-specific | -2.01696 |
| USPL1 | ubiquitin specific peptidase like 1 | -2.01544 |
