| Dataset | Carcinogenome Chemical Perturbation Carcinogenicity Signatures |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | DMSO perturbation at 24 h in HEPG2 (Carcinogenome) |
| Similar Terms | |
| Downloads & Tools |
70 genes differentially expressed following the CRCGN013_HEPG2_24H:F09 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CIAO3 | cytosolic iron-sulfur assembly component 3 | 6.13015 |
| ATP11B | ATPase, class VI, type 11B | 3.95546 |
| LOC122526780 | uncharacterized LOC122526780 | 3.70364 |
| GSTZ1 | glutathione S-transferase zeta 1 | 3.49685 |
| STK10 | serine/threonine kinase 10 | 3.4483 |
| STXBP2 | syntaxin binding protein 2 | 3.43726 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 3.3095 |
| GPER1 | G protein-coupled estrogen receptor 1 | 3.27331 |
| MAST2 | microtubule associated serine/threonine kinase 2 | 3.25673 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | 3.18934 |
| LPAR2 | lysophosphatidic acid receptor 2 | 2.8015 |
| TBXA2R | thromboxane A2 receptor | 2.67228 |
| MPDU1 | mannose-P-dolichol utilization defect 1 | 2.52416 |
| CHRNG | cholinergic receptor, nicotinic, gamma (muscle) | 2.43809 |
| NUDT9 | nudix (nucleoside diphosphate linked moiety X)-type motif 9 | 2.41841 |
| TPSG1 | tryptase gamma 1 | 2.40708 |
| TBP | TATA box binding protein | 2.37782 |
| DNMT3A | DNA (cytosine-5-)-methyltransferase 3 alpha | 2.36981 |
| NFATC4 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 2.33626 |
| GPT | glutamic-pyruvate transaminase (alanine aminotransferase) | 2.22163 |
| NANOS2 | nanos homolog 2 (Drosophila) | 2.20301 |
| KDM8 | lysine (K)-specific demethylase 8 | 2.15732 |
| EIF2B4 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 2.15083 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | 2.13305 |
| SOCS2 | suppressor of cytokine signaling 2 | 2.12672 |
| CSH2 | chorionic somatomammotropin hormone 2 | 2.12235 |
| GEMIN7 | gem (nuclear organelle) associated protein 7 | 2.1111 |
| PIWIL2 | piwi-like RNA-mediated gene silencing 2 | 2.10014 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 2.08647 |
| NR1H2 | nuclear receptor subfamily 1, group H, member 2 | 2.08273 |
| PMCH | pro-melanin-concentrating hormone | 2.07781 |
| RLBP1 | retinaldehyde binding protein 1 | 2.05575 |
| HYOU1 | hypoxia up-regulated 1 | 2.04998 |
| CEACAM4 | carcinoembryonic antigen-related cell adhesion molecule 4 | 2.04057 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor | 2.0279 |
| DOC2B | double C2-like domains, beta | 2.02379 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LDHD | lactate dehydrogenase D | -8.43746 |
| MAPK13 | mitogen-activated protein kinase 13 | -6.46076 |
| IARS2 | isoleucyl-tRNA synthetase 2, mitochondrial | -5.85501 |
| PCNA | proliferating cell nuclear antigen | -5.4363 |
| GNAS | GNAS complex locus | -3.83437 |
| EGF | epidermal growth factor | -3.81057 |
| VAT1 | vesicle amine transport 1 | -3.79956 |
| DERA | deoxyribose-phosphate aldolase (putative) | -3.70557 |
| MRPS2 | mitochondrial ribosomal protein S2 | -3.43694 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -3.37077 |
| NGRN | neugrin, neurite outgrowth associated | -3.11906 |
| ZNF586 | zinc finger protein 586 | -2.96646 |
| TLE1 | transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) | -2.92258 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -2.79072 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | -2.74098 |
| PRPF4 | pre-mRNA processing factor 4 | -2.67489 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | -2.60829 |
| FGFR4 | fibroblast growth factor receptor 4 | -2.53165 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -2.5098 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -2.50344 |
| SNX11 | sorting nexin 11 | -2.49627 |
| HLA-DMA | major histocompatibility complex, class II, DM alpha | -2.37575 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | -2.37529 |
| CCNB1 | cyclin B1 | -2.37242 |
| NBEA | neurobeachin | -2.33581 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | -2.31386 |
| DOCK4 | dedicator of cytokinesis 4 | -2.19664 |
| SLC35F2 | solute carrier family 35, member F2 | -2.17147 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | -2.14736 |
| SLIT2 | slit homolog 2 (Drosophila) | -2.10977 |
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 | -2.10808 |
| KIAA0232 | KIAA0232 | -2.0991 |
| PPP1R26 | protein phosphatase 1, regulatory subunit 26 | -2.02751 |
| PNMA8A | PNMA family member 8A | -2.00453 |
