CRCGN013_HEPG2_24H:F10 Gene Set
Genes
55 genes differentially expressed following the CRCGN013_HEPG2_24H:F10 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
10.0
|
|
GPER1
|
G protein-coupled estrogen receptor 1
|
5.47345
|
|
NUDT9
|
nudix (nucleoside diphosphate linked moiety X)-type motif 9
|
4.89502
|
|
GSTZ1
|
glutathione S-transferase zeta 1
|
4.83248
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
4.47916
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
3.96821
|
|
LCN2
|
lipocalin 2
|
3.9184
|
|
ADO
|
2-aminoethanethiol (cysteamine) dioxygenase
|
3.88588
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
3.84211
|
|
TBP
|
TATA box binding protein
|
3.80864
|
|
MCM3
|
minichromosome maintenance complex component 3
|
3.65732
|
|
UBQLN2
|
ubiquilin 2
|
3.62497
|
|
PACSIN3
|
protein kinase C and casein kinase substrate in neurons 3
|
3.60053
|
|
PHKA1
|
phosphorylase kinase, alpha 1 (muscle)
|
3.31529
|
|
JADE2
|
jade family PHD finger 2
|
3.24263
|
|
INTS3
|
integrator complex subunit 3
|
3.24162
|
|
E2F2
|
E2F transcription factor 2
|
3.09667
|
|
MAP7
|
microtubule-associated protein 7
|
2.83589
|
|
HSPA1A
|
heat shock 70kDa protein 1A
|
2.68897
|
|
CEBPZ
|
CCAAT/enhancer binding protein (C/EBP), zeta
|
2.67837
|
|
MYLK
|
myosin light chain kinase
|
2.57387
|
|
SRC
|
SRC proto-oncogene, non-receptor tyrosine kinase
|
2.56615
|
|
NDN
|
necdin, melanoma antigen (MAGE) family member
|
2.4406
|
|
CHN1
|
chimerin 1
|
2.35936
|
|
GATA3
|
GATA binding protein 3
|
2.33767
|
|
TXNL4B
|
thioredoxin-like 4B
|
2.20666
|
|
CARMIL1
|
capping protein regulator and myosin 1 linker 1
|
2.15175
|
|
CSF2
|
colony stimulating factor 2 (granulocyte-macrophage)
|
2.11499
|
|
CEP57
|
centrosomal protein 57kDa
|
2.01179
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
SLC35F2
|
solute carrier family 35, member F2
|
-7.0592
|
|
HSPB1
|
heat shock 27kDa protein 1
|
-5.11805
|
|
VDAC1
|
voltage-dependent anion channel 1
|
-4.14821
|
|
CCNB1
|
cyclin B1
|
-4.05509
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-3.62233
|
|
PCNA
|
proliferating cell nuclear antigen
|
-3.47196
|
|
HMGCS1
|
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
|
-3.19776
|
|
EGF
|
epidermal growth factor
|
-3.01468
|
|
ADI1
|
acireductone dioxygenase 1
|
-2.84877
|
|
DUSP11
|
dual specificity phosphatase 11 (RNA/RNP complex 1-interacting)
|
-2.62249
|
|
TARBP1
|
TAR (HIV-1) RNA binding protein 1
|
-2.57082
|
|
KDM3A
|
lysine (K)-specific demethylase 3A
|
-2.52875
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-2.48107
|
|
FBXL12
|
F-box and leucine-rich repeat protein 12
|
-2.46636
|
|
SCAND1
|
SCAN domain containing 1
|
-2.45035
|
|
RPS5
|
ribosomal protein S5
|
-2.45002
|
|
PCK2
|
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
|
-2.22797
|
|
ACTR10
|
actin-related protein 10 homolog (S. cerevisiae)
|
-2.22004
|
|
USP6NL
|
USP6 N-terminal like
|
-2.21066
|
|
HLA-DMA
|
major histocompatibility complex, class II, DM alpha
|
-2.2034
|
|
PLEKHJ1
|
pleckstrin homology domain containing, family J member 1
|
-2.1758
|
|
ABHD17A
|
abhydrolase domain containing 17A
|
-2.17374
|
|
GNAS
|
GNAS complex locus
|
-2.13114
|
|
HSD17B11
|
hydroxysteroid (17-beta) dehydrogenase 11
|
-2.07118
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-2.04661
|
|
ALS2CL
|
ALS2 C-terminal like
|
-2.0041
|
