CRCGN013_HEPG2_24H:F12 Gene Set
Genes
33 genes differentially expressed following the CRCGN013_HEPG2_24H:F12 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
CXCL2
|
chemokine (C-X-C motif) ligand 2
|
4.63861
|
|
HERC6
|
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
|
3.7289
|
|
ZNF589
|
zinc finger protein 589
|
3.71165
|
|
HLA-DRA
|
major histocompatibility complex, class II, DR alpha
|
3.58502
|
|
MAP7
|
microtubule-associated protein 7
|
3.36014
|
|
SMARCD2
|
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
|
3.10247
|
|
DYNLT3
|
dynein, light chain, Tctex-type 3
|
2.72217
|
|
CDK19
|
cyclin-dependent kinase 19
|
2.57247
|
|
P4HTM
|
prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
|
2.55377
|
|
PPARG
|
peroxisome proliferator-activated receptor gamma
|
2.5358
|
|
ABCC5
|
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
|
2.24228
|
|
CHEK2
|
checkpoint kinase 2
|
2.19364
|
|
ABHD6
|
abhydrolase domain containing 6
|
2.15899
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.15546
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-6.9773
|
|
CCNB2
|
cyclin B2
|
-5.83687
|
|
PKIG
|
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
|
-4.21197
|
|
ZDHHC6
|
zinc finger, DHHC-type containing 6
|
-3.32866
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.18575
|
|
SLC7A5
|
solute carrier family 7 (amino acid transporter light chain, L system), member 5
|
-3.12723
|
|
RAI14
|
retinoic acid induced 14
|
-2.99582
|
|
PCNA
|
proliferating cell nuclear antigen
|
-2.96541
|
|
WASHC4
|
WASH complex subunit 4
|
-2.93071
|
|
SLC35F2
|
solute carrier family 35, member F2
|
-2.92539
|
|
RFC2
|
replication factor C (activator 1) 2, 40kDa
|
-2.82529
|
|
ITGAE
|
integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
|
-2.76619
|
|
ITFG1
|
integrin alpha FG-GAP repeat containing 1
|
-2.72736
|
|
LDHD
|
lactate dehydrogenase D
|
-2.68876
|
|
FASTKD5
|
FAST kinase domains 5
|
-2.61039
|
|
CDC25B
|
cell division cycle 25B
|
-2.53736
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.4242
|
|
ABCF3
|
ATP-binding cassette, sub-family F (GCN20), member 3
|
-2.23274
|
|
GNAS
|
GNAS complex locus
|
-2.13384
|
