CRCGN013_HEPG2_24H:F14 Gene Set
Genes
35 genes differentially expressed following the CRCGN013_HEPG2_24H:F14 small molecule perturbation from the Carcinogenome Chemical Perturbation Carcinogenicity Signatures dataset.
increased expression
| Symbol |
Name |
Standardized Value |
|
UBQLN2
|
ubiquilin 2
|
4.22504
|
|
NOSIP
|
nitric oxide synthase interacting protein
|
3.94505
|
|
TIAM1
|
T-cell lymphoma invasion and metastasis 1
|
3.80257
|
|
LCN2
|
lipocalin 2
|
3.63261
|
|
RPP38
|
ribonuclease P/MRP 38kDa subunit
|
3.1534
|
|
INTS3
|
integrator complex subunit 3
|
3.04551
|
|
IKZF1
|
IKAROS family zinc finger 1 (Ikaros)
|
2.93656
|
|
CTSL
|
cathepsin L
|
2.67413
|
|
SSBP2
|
single-stranded DNA binding protein 2
|
2.62315
|
|
MAP7
|
microtubule-associated protein 7
|
2.5737
|
|
PSMB8
|
proteasome (prosome, macropain) subunit, beta type, 8
|
2.3987
|
|
NSDHL
|
NAD(P) dependent steroid dehydrogenase-like
|
2.26264
|
|
RXYLT1
|
ribitol xylosyltransferase 1
|
2.14385
|
|
EPN2
|
epsin 2
|
2.14205
|
|
CDC45
|
cell division cycle 45
|
2.06783
|
|
BAD
|
BCL2-associated agonist of cell death
|
2.03297
|
|
DDX10
|
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
|
2.0306
|
decreased expression
| Symbol |
Name |
Standardized Value |
|
ZNF586
|
zinc finger protein 586
|
-3.94635
|
|
OXA1L
|
oxidase (cytochrome c) assembly 1-like
|
-3.91123
|
|
IARS2
|
isoleucyl-tRNA synthetase 2, mitochondrial
|
-3.8751
|
|
CDKN1B
|
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
|
-3.31179
|
|
ST6GALNAC2
|
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2
|
-3.2347
|
|
CDC20
|
cell division cycle 20
|
-3.21548
|
|
ACOT9
|
acyl-CoA thioesterase 9
|
-3.16986
|
|
GDF15
|
growth differentiation factor 15
|
-2.7807
|
|
C2CD5
|
C2 calcium-dependent domain containing 5
|
-2.75273
|
|
MRPS16
|
mitochondrial ribosomal protein S16
|
-2.64993
|
|
DHRS7
|
dehydrogenase/reductase (SDR family) member 7
|
-2.62287
|
|
YTHDF1
|
YTH N(6)-methyladenosine RNA binding protein 1
|
-2.56365
|
|
MAP4K4
|
mitogen-activated protein kinase kinase kinase kinase 4
|
-2.41261
|
|
EIF5
|
eukaryotic translation initiation factor 5
|
-2.38693
|
|
DNM1L
|
dynamin 1-like
|
-2.36745
|
|
CHEK1
|
checkpoint kinase 1
|
-2.0722
|
|
EGF
|
epidermal growth factor
|
-2.06378
|
|
PRDM8
|
PR domain containing 8
|
-2.00224
|
